Associations Between Sarcopenia, Intramuscular Fat, Mental/Physical Function and Brain Atrophy: An Imaging and Machine Learning Approach

Research Opportunity
PhD students, Masters by Research, Honours students
Number of Honour Places Available
1
Number of Master Places Available
1
Department / Centre
Medicine and Radiology
Location
Western Health
Primary Supervisor Email Number Webpage
Professor Gustavo Duque gustavo.duque@unimelb.edu.au Personal web page
Co-supervisor Email Number Webpage
Dr Ebrahim Bani Hassan ebrahim.bani@unimelb.edu.au Personal web page

Summary Through a collaboration between AIMSS and our co-investigators in Norway we will quantify the volume of muscles of interest and the volume of intra/inter-muscular adipose tissue (IMAT) on MRI images of older adults.

Project Details

The research question is whether brain atrophy can lead muscle atrophy, or weakness, inactivity and loss of brain stimulation due to sarcopenia can cause cognition and brain volume decline. Muscle and IMAT volumes will be used as predictors of physical and nervous functions. Also, muscle and IMAT volumes will be correlated with the general and compartmental brain volumes to re-test the hypothesis that muscle decline and IMAT expansion is associated with brain atrophy and adverse events such as falls, cognitive decline and frailty.


School Research Themes

Ageing, Musculoskeletal



Research Opportunities

PhD students, Masters by Research, Honours students
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department / Centre

Medicine and Radiology

Research Node

Western Health

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