Associations Between Sarcopenia, Intramuscular Fat, Mental/Physical Function and Brain Atrophy: An Imaging and Machine Learning Approach
- Research Opportunity
- PhD students, Masters by Research, Honours students
- Number of Honour Places Available
- 1
- Number of Master Places Available
- 1
- Department / Centre
- Medicine and Radiology
- Location
- Western Health
| Primary Supervisor | Number | Webpage | |
|---|---|---|---|
| Professor Gustavo Duque | gustavo.duque@unimelb.edu.au | Personal web page |
| Co-supervisor | Number | Webpage | |
|---|---|---|---|
| Dr Ebrahim Bani Hassan | ebrahim.bani@unimelb.edu.au | Personal web page |
Summary Through a collaboration between AIMSS and our co-investigators in Norway we will quantify the volume of muscles of interest and the volume of intra/inter-muscular adipose tissue (IMAT) on MRI images of older adults.
Project Details
The research question is whether brain atrophy can lead muscle atrophy, or weakness, inactivity and loss of brain stimulation due to sarcopenia can cause cognition and brain volume decline. Muscle and IMAT volumes will be used as predictors of physical and nervous functions. Also, muscle and IMAT volumes will be correlated with the general and compartmental brain volumes to re-test the hypothesis that muscle decline and IMAT expansion is associated with brain atrophy and adverse events such as falls, cognitive decline and frailty.
School Research Themes
Research Opportunities
PhD students, Masters by Research, Honours students
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
Key Contact
For further information about this research, please contact a supervisor.
Department / Centre
Research Node
Western HealthMDHS Research library
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