Antibiotic stewardship and related polices impact on child health outcomes

Research Opportunity
PhD students
Department / Centre
Royal Children’s Hospital/Murdoch Childrens Research Institute
Primary Supervisor Email Number Webpage
Dr Yanhong Jessika Hu 0467895691 Personal web page
Co-supervisor Email Number Webpage
Prof Melissa Wake 0417506400 Personal web page

Summary Study associations of hospital antibiotic stewardship and prescribing policies among pregnancy and newborn and its impact on childhood health outcomes

Project Details

At least one in five pregnant women receive an antibiotic during pregnancy, and many more in the lead up to or during labour. There is a lack of detailed studies on polices’ impact of prescribed antibiotics on health and developmental outcomes in early childhood, both at the individual and the population level. There is evidence for example that antibiotic use during pregnancy influences the frequency of childhood infections. The consented ‘Generation Victoria’ cohort is targeting all 160,000 births over two years beginning in 2021 at all 70 birthing hospitals in the state of Victoria; it will eventually contain both GenV-collected exposure and outcomes data as well as linked clinical and administrative data, for example from the Pharmaceutical Benefits Scheme (PBS), Medicare Benefits Schedule (MBS), hospitals prescribing and neonatal health outcomes.
This PhD candidate will focus on:
- Map antibiotic prescribing guidelines and stewardship policies for pregnant women and newborns across Victoria’s 70 birthing hospitals.
- In a proof-of-principle analysis, study associations of hospital antibiotic stewardship and prescribing policies with pregnancy and newborn outcomes in the 70 hospitals over GenV’s first 6-12 months of operation. The landmark GenV platform thus offers immense opportunities to establish a career with leadership in pregnancy pharmacovigilance and child health research.

Faculty Research Themes

Child Health, Infection and Immunology, Neuroscience

School Research Themes

Child Health in Medicine, Neuroscience & Psychiatry, Women's Health, Infectious Diseases and Immunity

Research Opportunities

PhD students
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department / Centre


Research Node

Royal Children’s Hospital/Murdoch Childrens Research Institute

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