An anti-calcitonin receptor (CTR) antibody for detection of programmed cell death: the role of CTR in a novel adaptive response to cell stress

Research Opportunity
PhD students
Department / Centre
Austin Health
Primary Supervisor Email Number Webpage
Dr Peter Wookey 0419 633 146 Personal web page

Summary Programmed cell death (PCD) is an essential process in life.

Project Details

Programmed cell death (PCD) is an essential process in life. For apoptosis the sequelae of events resulting in PCD, include mitochondrial changes, exposure of phosphatidylserine, activation of caspases, etc.. Another key pathway is autophagy, initially a response to cell stress. We have found evidence of expression of CTR during the pre-apoptotic cell stress response. There are two common isoforms of human calcitonin receptor (CTR) which differ by an extra 16-amino acid insert in CTRb. We are exploring a role in pre-apoptotic cell stress, apoptosis and autophagy using unique antibodies developed here, including one antibody that binds the insert sequence.

Faculty Research Themes

Cancer, Neuroscience

School Research Themes

Cancer in Medicine, Neuroscience & Psychiatry, Cardiometabolic

Research Opportunities

PhD students
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department / Centre


Research Group / Unit / Centre

Research Node

Austin Health

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