A novel biomarker strategy to predict neurogenerative disease risk

Research Opportunity
PhD students, Masters by Research, Honours students, Post Doctor Researchers
Number of Honour Places Available
1
Department / Centre
Psychiatry
Primary Supervisor Email Number Webpage
Dr Samantha Loi samantha.loi@unimelb.edu.au 93428750 Personal web page
Co-supervisor Email Number Webpage
Professor Danny Hatters dhatters@unimelb.edu.au 8344 2530
Professor Dennis Velakoulis dennis.velakoulis@mh.org.au 93428750

Summary This project will examine the potential of a novel chemical probe as a biomarker of neurodegenerative disease risk.

Project Details

This project will examine the potential of a novel chemical probe as a biomarker of neurodegenerative disease risk. The probe has been shown in the Hatters laboratory to detect imbalances in protein quality control mechanisms in cultured cell models of neurodegenerative disease. Our hypothesis is that this probe can detect early stages of disease risk and has potential to identify imbalances arising before clinical presentation of disease. The scope of this project is to collect patient blood and then test blood cells (lymphocytes) for evidence of protein quality control imbalances using the chemical probe. Methods will include cell culture, flow cytometry, statistical analysis of data and would suit a student interested in biochemistry.



Faculty Research Themes

Neuroscience

School Research Themes

Neuroscience & Psychiatry



Research Opportunities

PhD students, Masters by Research, Honours students, Post Doctor Researchers
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department / Centre

Psychiatry


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