A novel biomarker strategy to predict neurogenerative disease risk
- Research Opportunity
- PhD students, Masters by Research, Honours students, Post Doctor Researchers
- Number of Honour Places Available
- 1
- Department / Centre
- Psychiatry
| Primary Supervisor | Number | Webpage | |
|---|---|---|---|
| Dr Samantha Loi | samantha.loi@unimelb.edu.au | 93428750 | Personal web page |
| Co-supervisor | Number | Webpage | |
|---|---|---|---|
| Professor Danny Hatters | dhatters@unimelb.edu.au | 8344 2530 | |
| Professor Dennis Velakoulis | dennis.velakoulis@mh.org.au | 93428750 |
Summary This project will examine the potential of a novel chemical probe as a biomarker of neurodegenerative disease risk.
Project Details
This project will examine the potential of a novel chemical probe as a biomarker of neurodegenerative disease risk. The probe has been shown in the Hatters laboratory to detect imbalances in protein quality control mechanisms in cultured cell models of neurodegenerative disease. Our hypothesis is that this probe can detect early stages of disease risk and has potential to identify imbalances arising before clinical presentation of disease. The scope of this project is to collect patient blood and then test blood cells (lymphocytes) for evidence of protein quality control imbalances using the chemical probe. Methods will include cell culture, flow cytometry, statistical analysis of data and would suit a student interested in biochemistry.
Faculty Research Themes
School Research Themes
Research Opportunities
PhD students, Masters by Research, Honours students, Post Doctor Researchers
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
Key Contact
For further information about this research, please contact a supervisor.
Department / Centre
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