A monoclonal antibody (mAb1F5) has been developed that identifies a unique marker, a membrane protein expressed by pericytes and meningeal cells
- Research Opportunity
- PhD students
- Department / Centre
- Medicine
- Location
- Austin Health
| Primary Supervisor | Number | Webpage | |
|---|---|---|---|
| Dr Peter Wookey | pwookey@unimelb.edu.au | 0419 633 146 | Personal web page |
Summary The expression pattern identified by a novel antibody has been characterised in a number of foetal and adult tissues including pericytes associated with tumour vasculature, meningeal cells of the foetal brain and osteoblasts of developing bone. These observations are consistent with the identification of a novel (growth) factor that would also play an important role in foetal development, neuron homeostasis and tumourogenesis. The proposed strategy for the identification of this target protein will include the purification of the protein/peptide from an osteoblast or meningeal cell line and sequencing of peptide fragments using proteomics and further molecular studies.
Faculty Research Themes
School Research Themes
Cancer in Medicine, Neuroscience & Psychiatry, Cardiometabolic
Research Opportunities
PhD students
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
Key Contact
For further information about this research, please contact a supervisor.
Department / Centre
Research Group / Unit / Centre
Cardiovascular and Tumourivascular Laboratory
Research Node
Austin HealthMDHS Research library
Explore by researcher, school, project or topic.