A monoclonal antibody (mAb1F5) has been developed that identifies the expression of a putative growth factor

Research Opportunity
PhD students, Honours students
Number of Honour Places Available
1
Department
Medicine and Radiology
Location
Austin Health
Primary Supervisor Email Number Webpage
Dr Peter Wookey pwookey@unimelb.edu.au 0419 633 146 Personal web page

Project Details

The expression pattern identified by a novel antibody has been characterised in a number of foetal and adult tissues including pericytes associated with tumour vasculature, meningeal cells of the foetal brain and osteoblasts of developing bone. These observations are consistent with the identification of a novel (growth) factor that would also play an important role in foetal development, neuron homeostasis and tumourogenesis. The proposed strategy for the identification of this target protein will include the purification of the protein/peptide from an osteoblast or meningeal cell line and sequencing of peptide fragments using proteomics and further molecular studies.



Faculty Research Themes

Cancer, Neuroscience

School Research Themes

Cancer in Medicine, Neuroscience & Psychiatry, Cardiometabolic



Research Opportunities

PhD students, Honours students
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Medicine and Radiology

Research Group / Unit / Centre

Cardiovascular and Tumourivascular Laboratory

Research Node

Austin Health

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