Musculoskeletal

Musculoskeletal diseases are identified as the second greatest cause of disability throughout the world and include conditions such as osteoporosis, sarcopenia and arthritis. Researchers are part of cross-functional and collaborative teams to study conditions related to disorders of the bone, muscle and joint for improvement in disease prevention and evidence-based care.

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Projects	Supervisor(s)	Department	Research Opportunity
BioFabrication of the osteo-chondral interface using multimodal 3D bioprinting	Prof Peter Choong Dr Cathal O’Connell	Surgery	Honours, Master of Biomedical Science
Bioink development for cartilage tissue engineering	Dr Romane Blanchard Dr Cathal O’Connell	Surgery	Honours, Master of Biomedical Science
Bone health and its long-term predictors post bone marrow transplantation	Prof David Ritchie Prof John Wark	Medicine and Radiology	Masters by Research, Honours, Master of Biomedical Science
Cellular Senescence as a Biomarker of Ageing	Dr Camilla Tuttle Professor Andrea Maier	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Comprehensive Geriatric Assessment in Geriatric Evaluation and Management Clinics	A/Professor Kwang Lim Professor Andrea Maier	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Controlled mechanical stimulation for cartilage regeneration modelling with 3D bioprinting techniques	Dr Carmine Onofrillo Dr Serena Duchi	Surgery	PhD, Masters by Research
Design of tensile strength tests for very soft materials	Dr Cathal O’Connell Dr Romane Blanchard	Surgery	PhD, Masters by Research, Honours, Master of Biomedical Science
Developing a patient reported outcome measure for joint replacement patients	A/Prof Michelle Dowsey Dr Darshini Ayton	Surgery	PhD, Master of Biomedical Science
Developing new therapies for musculoskeletal disease: Investigating the fundamental mechanisms of osteocyte mechanosensing	Dr Jonathan Gooi	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Development of a Brain-Machine-Interface Training Paradigm	Thomas Oxley Nicholas Opie	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Development of mechanical testing protocols for very soft tissues	Dr Cathal O’Connell Dr Romane Blanchard	Surgery	PhD, Masters by Research, Honours, Master of Biomedical Science
Development of scaffolds for restoration of myotendous junctions	A/Prof Robert Kapsa	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Diffusion properties in hydrogel materials	Dr Cathal O’Connell Dr Romane Blanchard	Surgery	PhD, Masters by Research, Honours, Master of Biomedical Science
Dynamic microfluidic in vitro differentiation of stem cells for cartilage regeneration in surgical 3D bioprinting	Dr Carmine Onofrillo Dr Serena Duchi	Surgery	PhD, Masters by Research
Elucidating molecular signalling pathways controlled by anti-inflammatory steroids	Dr. Adrian Achuthan	Medicine and Radiology	PhD, Masters by Research, Honours
Essence of Senescence	Dr Camilla Tuttle Prof Andrea Maier	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Evaluating the clinical and cost effectiveness of total joint replacement	Prof Philip Clarke A/Prof Michelle Dowsey	Surgery	PhD
Generation of an ex vivo regeneration model for 3D bioprinting applications	Dr Carmine Onofrillo Dr Serena Duchi	Surgery	PhD, Masters by Research
HDAC6 inhibitors as a treatment for Rett syndrome: Resolving neuronal trafficking deficits	Dr Nicole Van Bergen Professor John Christodoulou	Paediatrics	Honours
How does bone matrix composition determine bone strength?	A/Prof Natalie Sims	Medicine and Radiology	Honours, Master of Biomedical Science
How does bone matrix composition determine bone strength?	A/Prof Natalie Sims	Medicine and Radiology	Honours, Master of Biomedical Science
How does PTHrP stimulate bone formation?	A/Prof Natalie Sims	Medicine and Radiology	PhD
How does the C-terminus of parathyroid hormone-related protein modify intracellular signalling?	A/Prof Natalie Sims E/Prof TJ Martin	Medicine and Radiology	PhD
Inter- and intra-individual pattern of diseases	Dr Esmee Reijnierse Professor Andrea Maier	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Investigating the interaction between skeletal muscle and bone	Dr Jonathan Gooi	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Longitudinal analysis of health outcomes in 16-29 year old females	Prof Suzanne Garland Prof John Wark	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Molecular signalling pathways controlling gene expression during chronic disease progression	Dr. Adrian Achuthan	Medicine and Radiology	PhD, Masters by Research, Honours
Monitoring for atypical femoral fracture (AFF) risk	Dr Chris Yates Prof John Wark	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Muscle health and nutritional needs during recovery from acute disease – also offered as MBiomedSc	Dr Esmee Reijnierse Prof Andrea Maier	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Neural modelling of epileptic dynamics	Dr Andre Peterson	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Optimal Pain Assessment in Joint Replacement Patients	Adjunct A/Prof Maria Inacio A/Prof Michelle Dowsey	Surgery	PhD, Masters by Research
Physical Activities for Healthy Ageing	Professor Cassandra Szoeke Dr Steve Simpson Jr	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Predicting outcomes for people with knee osteoarthritis in general practice	Prof Jane Gunn A/Prof Michelle Dowsey	General Practice	PhD
Probing the complexity of cartilage using the Atomic Force Microscope	Dr Cathal O’Connell Dr Romane Blanchard	Surgery	Honours, Master of Biomedical Science
Proteostasis and Muscle Regeneration	Dr Camilla Tuttle Prof Andrea Maier	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Refining the comprehensive geriatric assessment	Dr Esmee Reijnierse Prof Andrea Maier	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Sarcopenia and nutritional needs during recovery from acute disease	Dr Esmee Reijnierse Professor Andrea Maier	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Social and physical activities in ageing women	Professor Cassandra Szoeke Dr Helen Brown	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Structural biology of proteins involved in bone diseases	Prof Michael Parker	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
The underestimated power of human muscle	Dr Camilla Tuttle Professor Andrea Maier	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
The actions of the hormone, calcitonin, on bone and calcium metabolism	A/Professor Rachel Davey	Medicine and Radiology	Honours
The blood pressure drop makes you fall	Dr Esmee Reijnierse Prof Andrea Maier	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
The intra-individual rate of ageing	Dr Esmee Reijnierse Professor Andrea Maier	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Towards a biological geriatric assessment	Dr Camilla Tuttle Professor Andrea Maier	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
Using health-related quality of life scores as predictor of outcomes and to advance health economic evaluation methodologies in lower limb arthroplasty patients	Michelle Dowsey Philip Clarke	Surgery	PhD
Vitamin D deficiency and balance	Professor Cassandra Szoeke Professor Meg Morris	Medicine and Radiology	PhD, Masters by Research, Honours, Master of Biomedical Science
What controls the development of strong cortical bone?	A/Prof Natalie Sims	Medicine and Radiology	PhD
What controls the development of strong cortical bone?	A/Prof Natalie Sims	Medicine and Radiology	PhD