Musculoskeletal

Musculoskeletal diseases are identified as the second greatest cause of disability throughout the world and include conditions such as osteoporosis, sarcopenia and arthritis. Researchers are part of cross-functional and collaborative teams to study conditions related to disorders of the bone, muscle and joint for improvement in disease prevention and evidence-based care.

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Projects Supervisor(s) Department Research Opportunity
A cytokine pathway in the control of inflammation and pain John Hamilton Medicine and Radiology PhD students
Adipocytes as Weapons of Bone Destruction: The bone as a War Zone Gustavo Duque Medicine and Radiology PhD students, Masters by Research, Honours students
Analysis of Synovial Fluid and Peripheral Blood Samples from Patients with Rheumatoid Arthritis and Using Patients with Osteoarthritis as Controls Keith Lim Medicine and Radiology PhD students, Masters by Research, Honours students
Associations Between Sarcopenia, Intramuscular Fat, Mental/Physical Function and Brain Atrophy: An Imaging and Machine Learning Approach Gustavo Duque Medicine and Radiology PhD students, Masters by Research, Honours students
Balance Gym for Falls Prevention in Older Adults Gustavo Duque Medicine and Radiology PhD students, Masters by Research, Honours students
Biofabrication of an in vitro 3D osteosarcoma model Claudia di Bella
Serena Duchi 		Surgery PhD students, Masters by Research, Honours students, Master of Biomedical Science
Bone Substrate Composition Affecting Bone Cell Formation, Function and Bone Turnover Damian Myers Medicine and Radiology PhD students, Masters by Research, Honours students
Cartilage regeneration for in surgical 3D bioprinting Claudia di Bella
Carmine Onofrillo 		Surgery PhD students, Masters by Research, Honours students, Master of Biomedical Science
CASE: Cartilage Analytic Screening Environment Claudia di Bella
Carmine Onofrillo 		Surgery PhD students, Masters by Research
Characterization of Osteosarcopenia in Older Persons: A Bench to Bedside Approach Gustavo Duque Medicine and Radiology PhD students, Masters by Research, Honours students
Controlled mechanical stimulation for cartilage regeneration modelling with 3D bioprinting techniques Carmine Onofrillo Surgery PhD students, Masters by Research
Dendritic cell cutaneous egression in Mycobacterium ulcerans infection John Hayman Clinical Pathology Honours students, Master of Biomedical Science
Development of Marrow Fat Quantification as a Predictor of Poor Outcomes in Osteosarcopenia Gustavo Duque Medicine and Radiology PhD students, Masters by Research, Honours students
Dynamic microfluidic in vitro differentiation of stem cells for cartilage regeneration in surgical 3D bioprinting Carmine Onofrillo Surgery PhD students, Masters by Research
Effect of HMB and Vitamin D Supplementation on osteosarcoPenia In oldeR pErsons (EMPIRE) Gustavo Duque Medicine and Radiology PhD students, Masters by Research, Honours students
Effects of Vitamin D Status on DEXA Femoral Neck BMD in Children and Adolescents Christine Rodda Medicine and Radiology PhD students, Masters by Research
Effects of Vitamin D Status on Forearm Fracture Healing Rates in Children and Adolescents: A Pilot Study Christine Rodda Medicine and Radiology PhD students, Masters by Research
Elucidating molecular signalling pathways controlled by anti-inflammatory steroids Adrian Achuthan Medicine and Radiology PhD students, Masters by Research, Honours students, Master of Biomedical Science
Elucidating the functional roles of CCL17 in obesity-associated osteoarthritis Adrian Achuthan Medicine and Radiology PhD students
Field tests for evaluation and prognostication in interstitial lung disease Yet Hong Khor Medicine and Radiology PhD students, Masters by Research, Honours students
Fighting disease with electricity: Vagus nerve stimulation as a treatment of arthritis Sophie Payne Medical Bionics Department Honours students
Generation of an ex vivo regeneration model for 3D bioprinting applications Carmine Onofrillo Surgery PhD students, Masters by Research
How are autophagic processes involved in bone mineralisation? Natalie Sims Medicine and Radiology PhD students, Honours students
How does the periosteum control bone width? Natalie Sims Medicine and Radiology Honours students
Inflammation-induced Osteosarcopenia: Mechanisms and Novel Treatments Kulmira Nurgali Medicine and Radiology PhD students, Masters by Research, Honours students
Investigating Lipotoxic Impacts of Fatty Acid Synthesis on: (1) Osteoblasts, and (2) Osteoclast, in Vitro and (3) Skeletal Muscle Damian Myers Medicine and Radiology PhD students, Masters by Research, Honours students
Investigating the Anabolic Effect Drugs (Picolinic Acid) on Osteocytes in Vitro Gustavo Duque Medicine and Radiology PhD students, Masters by Research, Honours students
Investigating the Rapamycin Effect on Induced-Palmitic osteocytes in Vitro Gustavo Duque Medicine and Radiology PhD students, Masters by Research, Honours students
Marrow Adipose Tissue Functions: Studying Lipotoxicity in Hip Replacement Candidates Gustavo Duque Medicine and Radiology PhD students, Masters by Research, Honours students
Mid-Thigh Bone and Muscle Mass Measurements as an Assessment Tool for Diagnosis of Osteoporosis/penia, Sarcopenia and Osteosarcopenia: A Longitudinal Validation Study Gustavo Duque Medicine and Radiology PhD students, Masters by Research, Honours students
Molecular signalling pathways controlling gene expression during chronic disease progression Adrian Achuthan Medicine and Radiology PhD students, Masters by Research, Honours students, Master of Biomedical Science
Neural modelling of epileptic dynamics Andre Peterson Medicine and Radiology PhD students, Masters by Research, Honours students, Master of Biomedical Science
Osteosarcopenia as a Geriatric Syndrome Gustavo Duque Medicine and Radiology PhD students, Masters by Research, Honours students
Osteosarcopenia assessment in resource-limited settings Jesse Zanker Medicine and Radiology Honours students
Osteosarcopenia in community-dwelling older adults attending the Falls and Fracture Clinic Gustavo Duque Medicine and Radiology PhD students, Masters by Research, Honours students
Osteosarcopenia in Older Adults Attending a Fracture Liaison Service David Scott Medicine and Radiology PhD students, Masters by Research
Pathology begins in the cells: Studying lipotoxic stress generated from adipocytes in bone and muscle cell cultures Damian Myers Medicine and Radiology PhD students, Masters by Research, Honours students
Pre-clinical Analysis of Effects of Lamin A Overexpression on Mesenchymal Stem Cell Differentiation into Myocytes Gustavo Duque Medicine and Radiology PhD students, Masters by Research, Honours students
Pre-Clinical Studies Identifying Novel Molecular Regulators of Skeletal Muscle Growth and Atrophy Alan Hayes Medicine and Radiology PhD students, Masters by Research, Honours students
Predicting Disability and Frailty in Older Persons: The Western Osteosarcopenia and Frailty (WOSF) Study Gustavo Duque Medicine and Radiology PhD students, Masters by Research, Honours students
Refining the comprehensive geriatric assessment Andrea Maier Medicine and Radiology PhD students, Masters by Research, Honours students
Structural biology of proteins involved in bone diseases Brett Bennetts Medicine and Radiology PhD students, Masters by Research, Honours students, Master of Biomedical Science
The Correlation between Knee Effusions and Clinical Presentation in Patients with Knee Osteoarthritis Keith Lim Medicine and Radiology PhD students, Masters by Research, Honours students
The role of CCL17 in osteoarthritis Kevin Lee Medicine and Radiology PhD students, Masters by Research, Honours students
Treatment outcome in older lung cancer patients: does the biological age predict it? Andrea Maier Medicine and Radiology PhD students, Masters by Research, Honours students
Use of tools to detect medication related problems in emergency departments Elizabeth Manias Psychiatry Honours students, Master of Biomedical Science
Using Marrow Adipose Tissue to Diagnose Osteoporosis and Predict Fragility Fractures Gustavo Duque Medicine and Radiology PhD students, Masters by Research, Honours students
Using Wearable Activity Trackers to Monitor Physical Activity in Older Adults Undergoing Exercise Interventions for Falls David Scott Medicine and Radiology PhD students, Masters by Research
Vascular remodeling in patients with Mycobacterium ulcerans infection and its effect on wound healing John Hayman Clinical Pathology Honours students, Master of Biomedical Science
Vitamin D deficiency and balance Monique Stagnitti Medicine and Radiology
What controls the development of strong cortical bone? Natalie Sims Medicine and Radiology PhD students, Honours students
Your Muscles Matter – The Sarcopenia Study Alan Hayes Medicine and Radiology PhD students, Masters by Research, Honours students