Musculoskeletal

Musculoskeletal diseases are identified as the second greatest cause of disability throughout the world and include conditions such as osteoporosis, sarcopenia and arthritis. Researchers are part of cross-functional and collaborative teams to study conditions related to disorders of the bone, muscle and joint for improvement in disease prevention and evidence-based care.

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Projects Supervisor(s) Department Research Opportunity
A cytokine pathway in the control of inflammation and pain John Hamilton Medicine PhD students
Adipocytes as Weapons of Bone Destruction: The bone as a War Zone Gustavo Duque Medicine PhD students, Masters by Research
Analysis of Synovial Fluid and Peripheral Blood Samples from Patients with Rheumatoid Arthritis and Using Patients with Osteoarthritis as Controls Keith Lim Medicine PhD students, Masters by Research
Associations Between Sarcopenia, Intramuscular Fat, Mental/Physical Function and Brain Atrophy: An Imaging and Machine Learning Approach Gustavo Duque Medicine PhD students, Masters by Research
Balance Gym for Falls Prevention in Older Adults Gustavo Duque Medicine PhD students, Masters by Research
Biofabrication of an in vitro 3D osteosarcoma model Claudia di Bella
Serena Duchi 		Surgery PhD students, Masters by Research
Bone Substrate Composition Affecting Bone Cell Formation, Function and Bone Turnover Damian Myers Medicine PhD students, Masters by Research
CASE: Cartilage Analytic Screening Environment Claudia di Bella
Carmine Onofrillo 		Surgery PhD students, Masters by Research
Characterization of Osteosarcopenia in Older Persons: A Bench to Bedside Approach Gustavo Duque Medicine PhD students, Masters by Research
Controlled mechanical stimulation for cartilage regeneration modelling with 3D bioprinting techniques Carmine Onofrillo Surgery PhD students, Masters by Research
Development of Marrow Fat Quantification as a Predictor of Poor Outcomes in Osteosarcopenia Gustavo Duque Medicine PhD students, Masters by Research
Dynamic microfluidic in vitro differentiation of stem cells for cartilage regeneration in surgical 3D bioprinting Carmine Onofrillo Surgery PhD students, Masters by Research
Effect of HMB and Vitamin D Supplementation on osteosarcoPenia In oldeR pErsons (EMPIRE) Gustavo Duque Medicine PhD students, Masters by Research
Effects of Vitamin D Status on DEXA Femoral Neck BMD in Children and Adolescents Christine Rodda Medicine PhD students, Masters by Research
Effects of Vitamin D Status on Forearm Fracture Healing Rates in Children and Adolescents: A Pilot Study Christine Rodda Medicine PhD students, Masters by Research
Elucidating molecular signalling pathways controlled by anti-inflammatory steroids Adrian Achuthan Medicine PhD students, Masters by Research
Exploring how a high salt diet promotes bone destruction through immune cell activation Andrew Murphy Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students
Generation of an ex vivo regeneration model for 3D bioprinting applications Carmine Onofrillo Surgery PhD students, Masters by Research
How are autophagic processes involved in bone mineralisation? Natalie Sims Medicine PhD students
Inflammation-induced Osteosarcopenia: Mechanisms and Novel Treatments Kulmira Nurgali Medicine PhD students, Masters by Research
Inflammatory cytokines involved in obesity and osteoarthritis Kevin Lee Medicine PhD students, Masters by Research, Honours students, Post Doctor Researchers
Investigating Lipotoxic Impacts of Fatty Acid Synthesis on: (1) Osteoblasts, and (2) Osteoclast, in Vitro and (3) Skeletal Muscle Damian Myers Medicine PhD students, Masters by Research
Investigating the Anabolic Effect Drugs (Picolinic Acid) on Osteocytes in Vitro Gustavo Duque Medicine PhD students, Masters by Research
Investigating the Rapamycin Effect on Induced-Palmitic osteocytes in Vitro Gustavo Duque Medicine PhD students, Masters by Research
Marrow Adipose Tissue Functions: Studying Lipotoxicity in Hip Replacement Candidates Gustavo Duque Medicine PhD students, Masters by Research
Mid-Thigh Bone and Muscle Mass Measurements as an Assessment Tool for Diagnosis of Osteoporosis/penia, Sarcopenia and Osteosarcopenia: A Longitudinal Validation Study Gustavo Duque Medicine PhD students, Masters by Research
Molecular signalling pathways controlling gene expression during chronic disease progression Adrian Achuthan Medicine PhD students, Masters by Research
Osteosarcopenia as a Geriatric Syndrome Gustavo Duque Medicine PhD students, Masters by Research
Osteosarcopenia in community-dwelling older adults attending the Falls and Fracture Clinic Gustavo Duque Medicine PhD students, Masters by Research
Osteosarcopenia in Older Adults Attending a Fracture Liaison Service David Scott Medicine PhD students, Masters by Research
Pathology begins in the cells: Studying lipotoxic stress generated from adipocytes in bone and muscle cell cultures Damian Myers Medicine PhD students, Masters by Research
Pre-clinical Analysis of Effects of Lamin A Overexpression on Mesenchymal Stem Cell Differentiation into Myocytes Gustavo Duque Medicine PhD students, Masters by Research
Pre-Clinical Studies Identifying Novel Molecular Regulators of Skeletal Muscle Growth and Atrophy Alan Hayes Medicine PhD students, Masters by Research
Predicting Disability and Frailty in Older Persons: The Western Osteosarcopenia and Frailty (WOSF) Study Gustavo Duque Medicine PhD students, Masters by Research
Structural biology of proteins involved in bone diseases Brett Bennetts Medicine PhD students, Masters by Research
The Correlation between Knee Effusions and Clinical Presentation in Patients with Knee Osteoarthritis Keith Lim Medicine PhD students, Masters by Research
Using Marrow Adipose Tissue to Diagnose Osteoporosis and Predict Fragility Fractures Gustavo Duque Medicine PhD students, Masters by Research
Using Wearable Activity Trackers to Monitor Physical Activity in Older Adults Undergoing Exercise Interventions for Falls David Scott Medicine PhD students, Masters by Research
What controls the development of strong cortical bone? Natalie Sims Medicine PhD students
Your Muscles Matter – The Sarcopenia Study Alan Hayes Medicine PhD students, Masters by Research