Cardiometabolic

The School has a varied and strong research history into cardiometabolic diseases, covering conditions including diabetes, obesity, heart disease and different cardiac pathologies.  We conduct cutting-edge research, translating into practical outcomes through our strong links and embedding within leading hospitals in Melbourne, with many of our leading researchers also being clinical practitioners allowing them to directly apply their research in their clinical practice.

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Projects Supervisor(s) Department Research Opportunity
A randomised controlled trial of anti-androgen treatment for transgender women. Jeffrey Zajac Medicine and Radiology PhD
A randomised controlled trial of transdermal versus intramuscular testosterone therapy in transgender males Jeffrey Zajac Medicine and Radiology PhD
AMPK regulation of cholesterol metabolism Prof Bruce Kemp Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
AMPK regulation of lipid metabolism Prof Bruce Kemp Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
An anti-calcitonin receptor (CTR) antibody for the detection of programmed cell death: the role of CTR in a novel adaptive response in a pre-apoptotic mechanism Peter Wookey Medicine and Radiology Honours
Analysing the mutations in calcitonin receptor (CTR) mRNA transcripts, and identifying the isoforms and polymorphisms of CTR expressed in high grade glioma cell lines from glioblastoma Peter Medicine and Radiology Honours
Arterial coronary artery bypass surgery Alistair Royse
Colin Royse
Surgery PhD
Assessment of mitochondrial function in a mouse model of obesity and type 2 diabetes Sof Andrikopoulos Medicine and Radiology Honours
Can preoperative focused cardiac ultrasound improve morbidity and mortality after emergency noncardiac surgery? a pilot RCT David Canty
Colin Royse
Surgery PhD, Masters by Research, Honours, Master of Biomedical Science
Cardioprotection with Nano-MDIVI-1 Dr Shiang (Max) Lim Surgery PhD, Masters by Research, Honours, Master of Biomedical Science
Cardiovascular Risk in Nephrotic Syndrome Dr Jonathan Mynard
Dr Catherine Quinlan
Paediatrics Honours
Characterisation of GLUT12 knockout mice Prof Bruce Kemp Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
Characterization of GPR35 in models of cardiac and renal disease Andrew Kompa
Amanda Edgley
Medicine and Radiology Honours, Master of Biomedical Science
Comparison of learning focused cardiac ultrasound between self-directed and proctored simulator teaching pf medical students David Canty
Colin Royse
Surgery Masters by Research, Honours, Master of Biomedical Science
Connecting a macro-vessel to a pre-vascularized scaffold A/Prof Geraldine Mitchell Surgery PhD, Masters by Research, Honours, Master of Biomedical Science
Creating transplantable human capillary networks derived from adult human stem cells A/Prof Geraldine Mitchell Surgery PhD, Masters by Research, Honours, Master of Biomedical Science
Effect of uraemic toxins of vascular reactivity Andrew Kompa Medicine and Radiology Honours, Master of Biomedical Science
Effects of Dichloroacetic Acid (DCA) on Exercise Performance in Patients with Heart Failure with Preserved Ejection Fraction (HFpEF): a Randomized, Placebo-Controlled, Cross-Over Trial Chris Neil Medicine and Radiology PhD, Masters by Research
Exploring the microbiome and epigenetic links in obesity development Barbara Fam Medicine and Radiology Honours
Gene signatures of the ‘lymphaticome’ Dr Ramin Shayan
Dr Tara Karnezis
Surgery PhD, Masters by Research, Honours, Master of Biomedical Science
Genetic Analysis of Impaired beta Cell Function and Loss in Type 2 diabetes Sof Andrikopoulos Medicine and Radiology Honours
Goal-directed cognitive rehabilitation for self-management in older diabetic adults Alex Bahar-Fuchs Medicine and Radiology PhD, Masters by Research, Honours
High Dose Vitamin D and Post-Stroke Outcomes: A Randomized Controlled Trial Tissa Wijeratne Medicine and Radiology PhD, Masters by Research
How do HLA-DQ2 and DQ-8 increase the risk of people developing Type 1 diabetes? A/Prof Stuart Mannering Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
How do long noncoding RNAs (IncRNAs) regulate dendritic cell function and prevent autoimmune disease? Dr Tom Brodnicki Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
How does amino acid supply immune cell function and the development of autoimmune disease? Dr Tom Brodnicki Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
Identifying IL-17 receptor functions in pancreatic beta cells Helen Thomas Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
Inhibiting hypoxia and inflammation-induced damage to improve the outcomes of islet transplantation Helen Thomas Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
Investigating the effects of GM-CSF and M-CSF derived human macrophages on phagocytosing P. falciparum infected erythrocytes and cytokine production Adrian Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
Investigation of inter-arm blood pressure differences during paediatric exercise testing Dr Jonathan Mynard
Dr Michael Cheung
Paediatrics Honours
Modulating fibrosis and myocardial injury in Muscular Dystrophy Dr Adam Piers
A/Professor Salvatore Pepe
Paediatrics Honours
Modulation of CAMKK-Beta signalling by genetic variants Prof Bruce Kemp Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
Molecular mediators of gene:environment interactions underlying early life programming of cardiovascular and metabolic risk. Professor Richard Saffery
Dr David Burgner
Paediatrics Honours
New inhibitors for mitochondrial fission protein DRP1 Dr Jessica Holien
Dr Shiang (Max) Lim
Surgery PhD, Masters by Research, Honours, Master of Biomedical Science
Non-alcoholic fatty liver disease – characterising disease features in order to develop new therapies Amanda Edgley Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
Novel therapies for the treatment of cardiorenal syndrome Andrew Kompa Medicine and Radiology PhD
Peak exercise capacity in patients with a Fontan circulation Professor Yves D'Udekem
Dr Rachael Cordina
Paediatrics Honours
Post-translational regulation of AMPK Prof Bruce Kemp Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
Quantitating Corneal Density in Fabry Disease Kathy Nicholls Medicine and Radiology Honours
Refining the comprehensive geriatric assessment Kwang Lim Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
Repurposing JAK1/JAK2 inhibitors to treat Type 1 diabetes Tom Kay Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
Serial Evaluation of Cardiac and Vascular Function in Preeclampsia: Full Recovery or Persistent LV Contractile Impairment? Joanne Said Medicine and Radiology PhD, Masters by Research
Significance and Temporal Course of Advanced Echocardiographic Measurements of Left Ventricular Function in an Australian Cohort of Stage A Heart Failure, with High Baseline Cardiovascular Risk Chris Neil Medicine and Radiology PhD, Masters by Research, Honours
Small vessel disease as a marker for poorly controlled hypertension Judy Savige Medicine and Radiology Masters by Research, Honours, Master of Biomedical Science
Spermtyping – Single cell analysis of the generation of genetic diversity via DNA repair pathways Wayne Crismani Medicine and Radiology Honours, Master of Biomedical Science
Targeting inflammation and fibrosis for the treatment of retinal disease Roy Kong Medicine and Radiology PhD
The blood pressure drop makes you fall Julian Sacre Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
The economic impact of total arterial grafting in coronary arterial bypass graft surgery compared to arterial and venous grafting David Canty
Andrew Palmer
Surgery PhD, Masters by Research, Honours, Master of Biomedical Science
The intra-individual rate of ageing Andrea Maier Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
The radial artery in coronary bypass surgery Alistair Royse
Colin Royse
Surgery PhD
The role of an isoform of calcitonin receptor in glioma stem cells Peter Wookey Medicine and Radiology Honours
The role of nucleic acid sensing in triggering autoimmune diabetes Dr Tom Brodnicki Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
Therapeutic Inertia for Glycaemic and Cardiovascular Risk Factor Control in Patients with Type 2 Diabetes: A Real-world Electronic Medical Records Based Study Sanjoy Paul Medicine and Radiology PhD
Towards a biological geriatric assessment Camilla Tuttle Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
Treating fibrosis and inflammation to prevent end-organ damage in diabetes Roy Kong Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
Understanding how interferons are involved in autoimmune diabetes Dr Tom Brodnicki Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
Understanding if islet-infiltrating CTL can be identified in peripheral blood as biomarkers of Type 1 diabetes Dr Bala Krishnamurthy Medicine and Radiology PhD, Masters by Research, Honours, Master of Biomedical Science
Validation and Reliability of a Japanese ver. of PostopQRS Colin Royse
Surgery PhD