Cardiometabolic

The School has a varied and strong research history into cardiometabolic diseases, covering conditions including diabetes, obesity, heart disease and different cardiac pathologies.  We conduct cutting-edge research, translating into practical outcomes through our strong links and embedding within leading hospitals in Melbourne, with many of our leading researchers also being clinical practitioners allowing them to directly apply their research in their clinical practice.

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Projects Supervisor(s) Department Research Opportunity
: Unravelling the role of breast milk ether lipids in modulating immune function in early life Peter Meikle Baker Department of Cardiometabolic Health PhD students, Honours students
A monoclonal antibody (mAb1F5) has been developed that identifies a unique marker, a membrane protein expressed by pericytes and meningeal cells Peter Wookey Medicine PhD students
A novel approach in improving lipidomics throughput for population profiling Peter Meikle Baker Department of Cardiometabolic Health PhD students
Activated platelets targeted drug therapy Xiaowei Wang Baker Department of Cardiometabolic Health PhD students, Masters by Research
An anti-calcitonin receptor (CTR) antibody for detection of programmed cell death: the role of CTR in a novel adaptive response to cell stress Peter Wookey Medicine PhD students
An antibody (mAb2E1) that detects a novel, high molecular weight surrogate ligand of calcitonin receptor is detected in malignant glioma cells, developing brain and bone, and an osteosarcoma cell line Peter J Wookey Medicine PhD students
Application of computational biology approaches to identify and develop biomarkers to predict pregnancy disorders and guide clinical practice. Eva Dimitriadis Obstetrics and Gynaecology PhD students, Masters by Research
Artificial intelligence system to detect eye and cardiovascular diseases Mingguang He Surgery PhD students, Masters by Research
Assessing the therapeutic effects of plasmalogen supplementation in a mouse model of heart failure Yow Keat Tham Baker Department of Cardiometabolic Health Honours students
Brain storming therapeutics for neurodegeneration with novel research models Brian Drew Baker Department of Cardiometabolic Health PhD students, Honours students
Cellular and Molecular Mechanisms Driving Anthracycline-Induced Cardiotoxicity in Children Alexander Pinto Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students, Master of Biomedical Science, Post Doctor Researchers
Cellular and Molecular Mechanisms Driving Anthracycline-Induced Cardiotoxicity in Children Alexander Pinto Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students, Master of Biomedical Science
Common severe childhood infections, innate inflammatory responses and cardiometabolic risk: The VASCular changes aFter INfectious Diseases (VASCFIND) study David Burgner Paediatrics PhD students
Detecting the tissue of origin of circulating cell free DNA Lachlan Coin Clinical Pathology Masters by Research
Developing nanoparticles for targeted theranostics delivery of drug and gene therapeutics Xiaowei Wang Baker Department of Cardiometabolic Health PhD students, Masters by Research
Developing platelet derived nanoparticles for targeted thrombolysis Karlheinz Peter Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students
Development and validation of a high throughput clinical lipidomics platform Peter Meikle Baker Department of Cardiometabolic Health PhD students, Masters by Research
Diagnosis and therapy of inflammatory diseases using molecular ultrasound imaging Xiaowei Wang Baker Department of Cardiometabolic Health PhD students, Masters by Research
Do short chain fatty acids prevent gut leakiness and enhanced haematopoiesis induced by a high salt diet? Andrew Murphy Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students
Does epicardial adipose tissue contribute to atrial fibrillation in endurance athletes? Erin Howden Baker Department of Cardiometabolic Health Honours students
Drug development for metabolic diseases Jon Oakhill Medicine PhD students
Engineering a tissue flap Geraldine Mitchell Surgery PhD students
Exploring how a high salt diet promotes bone destruction through immune cell activation Andrew Murphy Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students
Exploring how diabetes causes increased proliferation of haematopoietic stem cells carrying a mutation in DNMT3A Andrew Murphy Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students
Exploring the contribution of intrinsic lipids to immune cell development and function Andrew Murphy Baker Department of Cardiometabolic Health PhD students, Honours students
Exploring the therapeutic potential of protein phosphatases in cardiometabolic disease Kate Weeks Baker Department of Cardiometabolic Health Masters by Research, Honours students
Factors that determine islet antigen-specific T cell expansion before the onset of Type 1 diabetes Helen Thomas Medicine PhD students, Masters by Research
Future Health Today Changing the course of cardiovascular disease Jo-Anne Manski-Nankervis General Practice PhD students
Gene signatures of the ‘lymphaticome’ Dr Ramin Shayan
Tara Karnezis 		Surgery PhD students, Masters by Research
Genomics of asthma mortality due to thunderstorm asthma Jo Douglass Medicine PhD students, Honours students
Heart Health in Women: Role of Physical Activity to Prevent Cardiovascular Disease Erin Howden Baker Department of Cardiometabolic Health PhD students
Identification of additional markers of ferroptosis with mass spectrometry Peter Meikle Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students
Identifying circadian clock and mineralocorticoid receptor (MR) interactions in heart disease Morag Young Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students, Master of Biomedical Science, Post Doctor Researchers
Immunity, Chronic Inflammation and Cardiovascular Disease Karlheinz Peter Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students
Inhibition of microglia inflammation by AMPK for obesity treatment Sandra Galic Medicine PhD students
Integration of population level ‘omics data to target cardiometabolic disease Peter Meikle Baker Department of Cardiometabolic Health PhD students, Honours students
Investigating a novel mechanism for improving beta-cell function in type 2 diabetes Kim Loh Medicine PhD students
Investigating cardiovascular disease in Friedreich's ataxia using human induced pluripotent stem cells Shiang (Max) Lim Surgery PhD students
Lifestyle Factors and Cognitive Health Cassandra Szoeke Medicine PhD students, Masters by Research
Lipidomic Profiling of Atrial Fibrillation Progression in a Murine Model Yow Keat Tham Baker Department of Cardiometabolic Health Honours students
Lipoproteins and Cardiovascular Risk from Mid- to Late-life in Women Alexandra Gorelik Medicine PhD students
Mechanotransduction in blood cells and consequences for thrombosis and inflammation Karlheinz Peter Baker Department of Cardiometabolic Health PhD students, Masters by Research
Mineralocorticoid receptor activation pathways in macrophages ; new mechanisms of heart failure Morag Young Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students, Master of Biomedical Science, Post Doctor Researchers
Modelling cardiovascular diseases using human cardiac organoids Shiang Lim Surgery PhD students, Masters by Research
Non-alcoholic fatty liver disease – characterising disease features in order to develop new therapies Amanda Edgley Medicine PhD students, Masters by Research
Novel regenerative therapies in cardiovascular diseases Karlheinz Peter Baker Department of Cardiometabolic Health PhD students, Masters by Research
Novel therapies for atherosclerotic plaque stabilization Karlheinz Peter Baker Department of Cardiometabolic Health PhD students, Masters by Research
Novel therapies for the treatment of cardiorenal syndrome Andrew Kompa Medicine PhD students
Nuclear receptor co-regulators in heart disease and inflammation; new targets for fine-tuning receptor actions in health and disease Morag Young Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students, Master of Biomedical Science, Post Doctor Researchers
Plasmalogen modulation as a therapeutic approach for fatty liver disease Peter Meikle Baker Department of Cardiometabolic Health PhD students, Honours students
Sex and the broken heart: sex-specific mechanisms driving heart failure Alexander Pinto Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students, Master of Biomedical Science
Sympathetic activation in adults with inadequate sleep Stephanie Yiallourou Baker Department of Cardiometabolic Health PhD students, Masters by Research
Targeting inflammation and fibrosis for the treatment of retinal disease Roy Kong Medicine PhD students
Targeting Pyroptosis to improve diabetic cardiovascular disease. Judy de Haan Baker Department of Cardiometabolic Health Honours students
The cellular fuel gauge: Novel mechanisms of metabolic control Jon Oakhill Medicine PhD students
The development of anti-NPY1 receptor antibodies for research into and treatment of cardiovascular diseases and cancer Peter J Wookey Medicine PhD students
The effect of ageing and sex differences on heart recovery following a heart attack Anna Calkin Baker Department of Cardiometabolic Health Honours students
The role of AMP-activated kinase in suppressing atherosclerosis Kim Loh Medicine PhD students
Treating fibrosis and inflammation to prevent end-organ damage in diabetes Roy Kong Medicine PhD students, Masters by Research
Type I interferon as a novel endogenous trigger of trained immunity Andrew Fleetwood Baker Department of Cardiometabolic Health PhD students
Understanding how Type 17 immunity and IL-17 cytokines regulate Type 1 diabetes Andrew Sutherland Medicine PhD students
Understanding the role of the circadian molecular clock in the development of dilated cardiac myopathy and atrial fibrillation. Morag Young Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students, Master of Biomedical Science, Post Doctor Researchers
Understanding the role of the mineralocorticoid receptor in diabetic cardiac myopathy? Morag Young Baker Department of Cardiometabolic Health PhD students, Honours students, Master of Biomedical Science
Unravelling the causes of persistent exercise intolerance in cancer survivors Steve Foulkes Baker Department of Cardiometabolic Health Honours students
Using the JAK1/JAK2 Inhibitor Baricitinib to treat new-onset Type 1 diabetes Helen Thomas Medicine PhD students, Masters by Research
Validation of 4D Flow with Exercise using CMR Ben Costello Baker Department of Cardiometabolic Health Honours students
What are antigens/epitopes are recognized in by islet-infiltrating CD8+ T cells in people with type 1 diabetes? Stuart Mannering Medicine PhD students