Cardiometabolic

The School has a varied and strong research history into cardiometabolic diseases, covering conditions including diabetes, obesity, heart disease and different cardiac pathologies.  We conduct cutting-edge research, translating into practical outcomes through our strong links and embedding within leading hospitals in Melbourne, with many of our leading researchers also being clinical practitioners allowing them to directly apply their research in their clinical practice.

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Projects Supervisor(s) Department Research Opportunity
A monoclonal antibody (mAb1F5) has been developed that identifies the expression of a putative growth factor Peter Wookey Medicine and Radiology PhD students, Honours students
Activated platelets targeted drug therapy Xiaowei Wang Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students
An anti-calcitonin receptor (CTR) antibody for the detection of programmed cell death: the role of CTR in a novel adaptive response in a pre-apoptotic mechanism Peter Wookey Medicine and Radiology PhD students, Honours students
An antibody that detects a high molecular weight surrogate ligand of calcitonin receptor is detected in malignant glioma cells and cell lines Peter J Wookey Medicine and Radiology PhD students, Honours students
An assessment and Validation of screening tools for Sleep Apnea in Singleton and Multiple Pregnancy Megan Rees Medicine and Radiology Honours students
Application of computational biology approaches to identify and develop biomarkers to predict pregnancy disorders and guide clinical practice. Eva Dimitriadis Obstetrics and Gynaecology PhD students, Masters by Research, Honours students
Artificial intelligence system to detect eye and cardiovascular diseases Mingguang He Surgery PhD students, Masters by Research
Characterising a New Target to Treat Fatty Liver Disease Anna Calkin Baker Department of Cardiometabolic Health Honours students
Characterization of GPR35 in models of cardiac and renal disease Andrew Kompa Medicine and Radiology Honours students, Master of Biomedical Science
Closed-loop bioelectrical neuromodulation control over bladder function Sophie Payne Medical Bionics Department Honours students, Master of Biomedical Science
Closing the Gap on Aboriginal Cardiovascular Health disparities- Using Big Data to understand the patient health journey Luke Burchill Medicine and Radiology Masters by Research
Common severe childhood infections, innate inflammatory responses and cardiometabolic risk: The VASCular changes aFter INfectious Diseases (VASCFIND) study David Burgner Paediatrics PhD students
Detecting the tissue of origin of circulating cell free DNA Lachlan Coin Clinical Pathology Masters by Research, Honours students
Diagnosis and therapy of inflammatory diseases using molecular ultrasound imaging Xiaowei Wang Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students
Drug development for metabolic diseases Jon Oakhill Medicine and Radiology PhD students, Honours students
Effect of uraemic toxins of vascular reactivity Andrew Kompa Medicine and Radiology Honours students, Master of Biomedical Science
Elucidating the functional roles of CCL17 in obesity-associated osteoarthritis Adrian Achuthan Medicine and Radiology PhD students
Engineering a tissue flap Geraldine Mitchell Surgery PhD students, Honours students
Exploring the causes of obesity development and obesity resistance Barbara Fam Medicine and Radiology Honours students
Factors that determine islet antigen-specific T cell expansion before the onset of Type 1 diabetes Helen Thomas Medicine and Radiology PhD students, Masters by Research, Honours students, Master of Biomedical Science
Field tests for evaluation and prognostication in interstitial lung disease Yet Hong Khor Medicine and Radiology PhD students, Masters by Research, Honours students
Future Health Today - health informatics Jo-Anne Manski-Nankervis General Practice PhD students
Future Health Today Changing the course of cardiovascular disease Jo-Anne Manski-Nankervis General Practice PhD students
Gene signatures of the ‘lymphaticome’ Dr Ramin Shayan
Tara Karnezis
Surgery PhD students, Masters by Research, Honours students, Master of Biomedical Science
Heart Health in Women: Role of Physical Activity to Prevent Cardiovascular Disease Erin Howden Baker Department of Cardiometabolic Health PhD students, Honours students
How does ageing affect the heart's response to heart attack? Anna Calkin Baker Department of Cardiometabolic Health Honours students
Immunity, Chronic Inflammation and Cardiovascular Disease Karlheinz Peter Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students
Inhibiting hypoxia and inflammation-induced damage to improve the outcomes of islet transplantation Michaela Waibel Medicine and Radiology Honours students, Master of Biomedical Science
Inhibition of microglia inflammation by AMPK for obesity treatment Sandra Galic Medicine and Radiology PhD students
Investigating a novel mechanism for improving beta-cell function in type 2 diabetes Kim Loh Medicine and Radiology PhD students, Honours students
Investigating cardiovascular disease in Friedreich's ataxia using human induced pluripotent stem cells Shiang (Max) Lim Surgery PhD students, Honours students, Master of Biomedical Science
Investigating the involvement of novel genes and pathways in islet beta-cell dysfunction and progression to Type 2 Diabetes Sof Andrikopoulos Medicine and Radiology Honours students
Investigating the role of OIP5-AS1 in cardiovascular diseases Brian Drew Baker Department of Cardiometabolic Health Honours students
Lifestyle Factors and Cognitive Health Cassandra Szoeke Medicine and Radiology PhD students, Masters by Research
Lipoproteins and Cardiovascular Risk from Mid- to Late-life in Women Alexandra Gorelik Medicine and Radiology PhD students, Master of Biomedical Science
Mechanotransduction in blood cells and consequences for thrombosis and inflammation Karlheinz Peter Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students
Modelling cardiovascular diseases using human cardiac organoids Shiang Lim Surgery PhD students, Masters by Research, Post Doctor Researchers
Non-alcoholic fatty liver disease – characterising disease features in order to develop new therapies Amanda Edgley Medicine and Radiology PhD students, Masters by Research, Honours students, Master of Biomedical Science
Novel therapies for the treatment of cardiorenal syndrome Andrew Kompa Medicine and Radiology PhD students
POPS (proactive care of older people undergoing surgery) Kwang Lim Medicine and Radiology Honours students, Master of Biomedical Science
Refining the comprehensive geriatric assessment Andrea Maier Medicine and Radiology PhD students, Masters by Research, Honours students
Regulation of ghrelin signalling by AMPK Sandra Galic Medicine and Radiology Honours students, Master of Biomedical Science
Simplifying clinical acid-base diagnosis in critical care David Story Medicine and Radiology Honours students, Master of Biomedical Science
Singing for breathing in people with severe non-malignant, chronic lung diseases Natasha Smallwood Medicine and Radiology PhD students
Spermtyping – Single cell analysis of the generation of genetic diversity via DNA repair pathways Wayne Crismani Medicine and Radiology Honours students, Master of Biomedical Science
Sympathetic activation in adults with inadequate sleep Stephanie Yiallourou Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students
Targeting inflammation and fibrosis for the treatment of retinal disease Roy Kong Medicine and Radiology PhD students
The cardiometabolic legacy of SARS-CoV-2 in longitudinal adolescents David Burgner Paediatrics PhD students
The cellular fuel gauge: Novel mechanisms of metabolic control Jon Oakhill Medicine and Radiology PhD students, Honours students
The development of anti-NPY1 receptor antibodies for research into and treatment of cardiovascular diseases and cancer Peter J Wookey Medicine and Radiology PhD students, Honours students
The role of AMP-activated kinase in suppressing atherosclerosis Kim Loh Medicine and Radiology PhD students, Honours students
Treating fibrosis and inflammation to prevent end-organ damage in diabetes Roy Kong Medicine and Radiology PhD students, Masters by Research, Honours students, Master of Biomedical Science
Treatment outcome in older lung cancer patients: does the biological age predict it? Andrea Maier Medicine and Radiology PhD students, Masters by Research, Honours students
Type I interferon as a novel endogenous trigger of trained immunity Andrew Fleetwood Baker Department of Cardiometabolic Health PhD students, Honours students
Type I interferon as a novel endogenous trigger of trained immunity Andrew Fleetwood Baker Department of Cardiometabolic Health Honours students
Understanding how Type 17 immunity and IL-17 cytokines regulate Type 1 diabetes Andrew Sutherland Medicine and Radiology PhD students, Honours students, Master of Biomedical Science
Use of tools to detect medication related problems in emergency departments Elizabeth Manias Psychiatry Honours students, Master of Biomedical Science
Using the JAK1/JAK2 Inhibitor Baricitinib to treat new-onset Type 1 diabetes Helen Thomas Medicine and Radiology PhD students, Masters by Research, Honours students, Master of Biomedical Science
What are antigens/epitopes are recognized in by islet-infiltrating CD8+ T cells in people with type 1 diabetes? Stuart Mannering Medicine and Radiology PhD students, Master of Biomedical Science
You are what you eat? The gut microbiome and its regulation of heart disease Yung-Chih Chen Baker Department of Cardiometabolic Health PhD students, Masters by Research, Honours students