Outer membrane vesicles and polymicrobial chronic disease

Research Opportunity
Honours, Master of Biomedical Science
Number of Honour Places Available
1
Number of Master Places Available
1
Department
Melbourne Dental School
Location
Bio21 Molecular Science and Biotechnology Institute,Royal Dental Hospital Melbourne
Primary Supervisor Email Number Webpage
Prof Stuart Dashper stuartgd@unimelb.edu.au
Co-supervisor Email Number Webpage
Dr Nada Slakeski
Dr Catherine Butler
Dr Samantha Byrne

Summary The project will provide you with opportunities to develop skills in confocal microscopy, molecular biology, anaerobic bacterial culture, and flow cytometry.

Project Details

Porphyromonas gingivalis and Treponema denticola display a range of synergistic behaviours including polymicrobial biofilm formation and development, and nutrient acquisition, which together enable them to cause chronic disease. Both bacteria produce and release outer membrane vesicles that preferentially bind to the other species. In this project you will determine how this binding occurs and the benefits to each species of binding outer membrane vesicles. The project will provide you with opportunities to develop skills in confocal microscopy, molecular biology, anaerobic bacterial culture, and flow cytometry.



Faculty Research Themes

Infection and Immunology

School Research Themes

Oral Infection and Immunity



Research Opportunities

Honours, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Melbourne Dental School

Research Node

Bio21 Molecular Science and Biotechnology Institute,Royal Dental Hospital Melbourne

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