Whole body analysis of human tissue-resident memory T cells

Research Opportunity
PhD
Department
Microbiology and Immunology
Location
Doherty Institute
Primary Supervisor Email Number Webpage
Dr Claire Gordon claire.gordon@unimelb.edu.au Personal web page
Co-supervisor Email Number Webpage
Associate Professor Laura Mackay lkmackay@unimelb.edu.au (03) 8344 8016 Personal web page

Summary Using our unique resource, this project will investigate the pathways that guide tissue-resident memory T cells (TRM) differentiation and maintenance in diverse tissue sites, with the overall goal of developing therapies and vaccines that manipulate TRM.

Project Details

The majority of T cell responses occur in tissues, however, our knowledge of human T cells is largely derived from blood. In collaboration with surgeons from Austin Health and DonateLife, we have access to samples from multiple lymphoid, visceral and barrier sites from research-consented organ donors. Using our unique resource, this project will investigate the pathways that guide tissue-resident memory T cells (TRM) differentiation and maintenance in diverse tissue sites, with the overall goal of developing therapies and vaccines that manipulate TRM.



Faculty Research Themes

Infection and Immunology

School Research Themes

Infection & Immunity



Research Opportunities

PhD
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Microbiology and Immunology

Research Group / Unit / Centre

Mackay (L) laboratory: Tissue-resident memory T cells; lymphocyte differentiation; peripheral immunity

Research Node

Doherty Institute

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