Using the TDP-43Q331K MND mouse model to determine the role of oligodendrocytes in disease
- Research Opportunity
- PhD students, Honours students
- Number of Honour Places Available
|Dr Samantha Bartonfirstname.lastname@example.org|
|Dr David Gonsalvez|
Summary Dr Barton's laboratory focusses on the motor neurone diseases and frontotemperal dementia, especially the role of non-neuronal cells like oligodendrocytes.
Oligodendrocytes have two essential roles in the CNS – to myelinate neurons and to provide metabolic support to axon through this myelin sheath. Given more than 95% of a neuron is its axon, and axons require myelination for normal function, impaired oligodendrocyte function would negatively impact on myelin formation and subsequent capacity to metabolically support neurons. Indeed, recent research from our lab and others has begun to implicate oligodendrocyte dysfunction in MND pathogenesis.
PhD students, Honours students
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
For further information about this research, please contact a supervisor.
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