Understanding the formation and secretion of mitochondria-derived vesicles
- Research Opportunity
- PhD students, Honours students, Master of Biomedical Science
- Number of Honour Places Available
- 1
- Number of Master Places Available
- 1
| Primary Supervisor | Number | Webpage | |
|---|---|---|---|
| Dr Magdalene Montgomery | magdalene.montgomery@unimelb.edu.au | Personal web page |
| Co-supervisor | Number | Webpage | |
|---|---|---|---|
| Dr Paula Miotto |
Summary Our group is interested in understanding the development of diabetic heart disease, with a particular focus on changes in mitochondrial function within the heart. We aim to define the metabolic pathways that drive cardiac mitochondrial dysfunction, with the longterm goal to identify new therapeutic angles for the treatment of heart disease.
Project Details
We made the novel discovery that the diabetic heart secretes mitochondrial components within vesicles as a means to dispose of damaged proteins and lipids. This project will assess the endocrine (i.e. secretory) function of the heart, with a focus on the formation and secretion of such mitochondria-derived vesicles (MDV). In addition, this project will investigate the systemic metabolic impact of these MDV in peripheral tissues.Research Opportunities
PhD students, Honours students, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
Key Contact
For further information about this research, please contact a supervisor.
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