tRNA synthetases enzymes as anti-malaria drug targets
- Department / Centre
- Biochemistry and Pharmacology
|A/Prof Stuart Ralphfirstname.lastname@example.org|
Summary "The Ralph group is interested in parasitic diseases, with a primary focus on the causative agent of severe malaria, Plasmodium falciparum. The burden of disease-causing parasites is particularly high in developing countries, and inadequate resources are directed towards the development of much needed treatments. Complete genome sequences are available for many of these parasites, so a wealth of data is available from which to search for potential targets for chemotherapeutic interventions. The group’s interests lie in identifying and characterising promising drug targets from Plasmodium falciparum and other parasites, as well as studying the modes of action and mechanisms of resistance for existing drugs. "