The use of bioactive maxtrices to treat traumatic brain injury

Research Opportunity
PhD students, Honours students, Master of Biomedical Science
Number of Honour Places Available
1
Number of Master Places Available
1
Primary Supervisor Email Number Webpage
Prof Peter Crack pcrack@unimelb.edu.au
Co-supervisor Email Number Webpage
Dr Juliet Taylor

Summary The Crack and Taylor group is run by Professor Peter Crack and Dr Juliet Taylor. The Neuropharmacology laboratory looks to understand how fundamental cellular signalling pathways can predispose the brain to exacerbated neurotrauma or neuropathology. In understanding how these pathways contribute to neural dysfunction we may be able to identify novel therapeutics that can be used to combat traumatic brain injury, Alzheimer’s disease and Parkinson’s disease.

Project Details

Traumatic brain injury (TBI) represents the major cause of death in young individuals in industrialised countries. Despite the improvement of neurosurgical procedures as well as critical care management, morbidity and mortality are still high and approximately 25% of these patients remain with permanent disabilities becoming a familiar, social and economic burden for society.  There are no treatments available for traumatic brain injury.  We are investigating the use of biomaterials to re-direct the brain's endogenous neural stem cells to facilitate neural repair after TBI.  This project will determine whether reconstructing functional neural circuitry via cell-based therapies represents a viable, alternative therapeutic strategy to improve clinical outcome. 



Research Opportunities

PhD students, Honours students, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.


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