The importance of IgA in the protection and control of infectious diseases

Research Opportunity
PhD, Masters by Research
Department
Microbiology and Immunology
Location
Doherty Institute
Primary Supervisor Email Number Webpage
Dr Amy Chung awchung@unimelb.edu.au (03) 8344 9938 Personal web page
Co-supervisor Email Number Webpage
Professor Stephen Kent skent@unimelb.edu.au (03) 8344 9939 Personal web page

Summary This project aims to further explore the mechanisms behind both the protective and immunomodulatory role of IgA in the control of HIV-1 and other infectious diseases.

Project Details

The human body produces more IgA than any other immunoglobulin, especially in mucosal secretions. However, the importance of IgA in both protection from HIV-1 and control of HIV-1 disease progression is highly controversial. Results from the only protective human HIV vaccine trial associated plasma IgA with reduced vaccine efficacy. In contrast, recent studies suggest that mucosal HIV-specific IgA may be protective. This project aims to further explore the mechanisms behind both the protective and immunomodulatory role of IgA in the control of HIV-1 and other infectious diseases.



Faculty Research Themes

Infection and Immunology

School Research Themes

Infection & Immunity



Research Opportunities

PhD, Masters by Research
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Microbiology and Immunology

Research Node

Doherty Institute

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