The importance of IgA in the protection and control of infectious diseases
- Research Opportunity
- PhD, Masters by Research
- Department
- Microbiology and Immunology
- Location
- Doherty Institute
| Primary Supervisor | Number | Webpage | |
|---|---|---|---|
| Dr Amy Chung | awchung@unimelb.edu.au | (03) 8344 9938 | Personal web page |
| Co-supervisor | Number | Webpage | |
|---|---|---|---|
| Professor Stephen Kent | skent@unimelb.edu.au | (03) 8344 9939 | Personal web page |
Summary This project aims to further explore the mechanisms behind both the protective and immunomodulatory role of IgA in the control of HIV-1 and other infectious diseases.
Project Details
The human body produces more IgA than any other immunoglobulin, especially in mucosal secretions. However, the importance of IgA in both protection from HIV-1 and control of HIV-1 disease progression is highly controversial. Results from the only protective human HIV vaccine trial associated plasma IgA with reduced vaccine efficacy. In contrast, recent studies suggest that mucosal HIV-specific IgA may be protective. This project aims to further explore the mechanisms behind both the protective and immunomodulatory role of IgA in the control of HIV-1 and other infectious diseases.
Faculty Research Themes
School Research Themes
Research Opportunities
PhD, Masters by Research
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
Key Contact
For further information about this research, please contact a supervisor.
Department
Research Node
Doherty InstituteMDHS Research library
Explore by researcher, school, project or topic.