Targeting peptide G protein-coupled receptors (GPCRs) for novel drug development

Summary The Bathgate lab focusses on understanding the interactions of peptide ligands with their G protein-coupled receptor (GPCR) targets for the development of peptide-based drugs and utilizing structure based drug design to develop novel therapeutics. He works closely with a number of pharmaceutical companies interested in the clinical development of drugs targeting receptors for peptides of the relaxin family. Projects are available on multiple therapeutically relevant GPCR targets with training in various techniques including peptide mimetic design, cell signalling assays, molecular pharmacology, structural biology and structure based drug design.