Structural biology in situ: Structure and function of bacterial secretion systems by cryo-EM
- Department / Centre
- Biochemistry and Pharmacology
|Dr Debnath Ghosalemail@example.com|
Summary We are interested in host-pathogen interaction particularly, how bacterial and viral pathogens utilize complex molecular machines to mediate infection. We use a range of structural (e.g. cryoEM, X-ray crystallography etc) and cell biology techniques to elucidate the structure and function of these molecular machines in situ, in their native context, inside ‘living’ cells.