Regeneration of lymphoid tissues

Research Opportunity
PhD, Masters by Research, Honours
Department
Microbiology and Immunology
Primary Supervisor Email Number Webpage
Associate Professor Scot Mueller smue@unimelb.edu.au (03) 8344 9044 Personal web page
Co-supervisor Email Number Webpage
Dr Yannick Alexandre yannick.alexandre@unimelb.edu.au 8344 0815

Summary Using new transgenic mice, this project will examine how lymphoid tissues expand and respond to infection, and how destruction of the tissue environment is regenerated by stromal cells.

Project Details

In the wake of infectious disease, or following lymph node removal, there is little evidence that lymph nodes can regenerate. Lymphoid organs are constructed from heterogeneous subsets of stromal cells that control immune cell survival and immune responses. Using new transgenic mice, this project will examine how lymphoid tissues expand and respond to infection, and how destruction of the tissue environment is regenerated by stromal cells. This will reveal new avenues to repair damage to lymphoid tissues and support immunity. Advanced multi-colour imaging, flow cytometry and molecular techniques will be used to address these questions.



Faculty Research Themes

Infection and Immunology

School Research Themes

Infection & Immunity



Research Opportunities

PhD, Masters by Research, Honours
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Microbiology and Immunology

Research Group / Unit / Centre

Mueller laboratory: Visualising the immune system in action


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