Population genomics of endemic Streptococcus pyogenes

Research Opportunity
PhD, Masters by Research, Honours
Department
Microbiology and Immunology
Location
Doherty Institute
Primary Supervisor Email Number Webpage
Dr Mark Davies mark.davies1@unimelb.edu.au (03) 9035 6519 Personal web page
Co-supervisor Email Number Webpage
Associate Professor Steven Tong steven.tong@mh.org.au (03) 9342 9406 Personal web page

Summary Through linking genomics with epidemiology, we aim to examine the evolutionary relationship between disease causing Streptococcus pyogenes clones within remote communities of Australia. Furthermore, we will apply statistical genetic models to identify genetic signatures associated with different disease stats and/or tissue tropism.

Project Details

Streptococcus pyogenes is one of the leading infectious disease agents in the world. The disease burden is alarmingly high within the Top End of Australia where the epidemiology of infection contrasts that of other geographical regions. Through linking genomics with epidemiology, we aim to examine the evolutionary relationship between disease causing Streptococcus pyogenes clones within remote communities of Australia. Furthermore, we will apply statistical genetic models to identify genetic signatures associated with different disease stats and/or tissue tropism. Unlocking these mysteries is key to informing public health intervention strategies including the development of informed vaccine programs within disease endemic regions.



Faculty Research Themes

Infection and Immunology

School Research Themes

Infection & Immunity



Research Opportunities

PhD, Masters by Research, Honours
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Microbiology and Immunology

Research Node

Doherty Institute

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