Novel master-regulators of B-cell biology

Research Opportunity
Masters by Research, Honours
Department
Microbiology and Immunology
Location
Doherty Institute
Primary Supervisor Email Number Webpage
Professor Fabienne Mackay fabienne.mackay@unimelb.edu.au (03) 8344 2726 Personal web page
Co-supervisor Email Number Webpage
Dr William Figgett william.figgett@unimelb.edu.au (03) 8344 1589 Personal web page
Dr Catherine Kennedy catherinek@unimelb.edu.au (03) 9035 8195 Personal web page

Summary This project aims to understand more about the function and mechanism of novel proteins and determine how they control fundamental B-cell biology.

Project Details

We generated CRISPR knock-out mouse lines in which putative B-cell regulating genes are specifically deleted. Changes in the B-cell repertoire are detectable using flow cytometry and immunofluorescence techniques. This project aims to understand more about the function and mechanism of these novel proteins and determine how they control fundamental B-cell biology.



Faculty Research Themes

Infection and Immunology

School Research Themes

Infection & Immunity



Research Opportunities

Masters by Research, Honours
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Microbiology and Immunology

Research Group / Unit / Centre

Mackay (F) laboratory: B lymphocytes, BAFF, autoimmunity and cancer

Research Node

Doherty Institute

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