Neuroinflammatory mechanisms in influenza viral infections

Research Opportunity
PhD students, Honours students, Master of Biomedical Science
Number of Honour Places Available
1
Number of Master Places Available
1
Primary Supervisor Email Number Webpage
Dr Alice McGovern alice.mcgovern@unimelb.edu.au
Co-supervisor Email Number Webpage
A/Prof Stuart Mazzone

Summary The Respiratory Sensory Neuroscience Laboratory is interested in the sensory neuron populations that innervate the airways and lungs and the brain circuits that process respiratory sensory information. We use transcriptomic profiling to better describe the molecular characteristics of respiratory sensory neurons, viral tract tracing and modern molecular physiology to understand the organisation of function circuits in the brain and human functional brain imaging to assess plasticity in the central nervous system in patients with disease.

Project Details

Influenza is a major cause of pulmonary disease.  We have discovered bidirectional interactions between the nervous and immune systems that are important for determining the severity of influenza infections.  This project will use surgical and molecular approaches in mice to further investigate the neural contributions to pulmonary inflammation during influenza.  Techniques include small animal surgeries, chemogenetics, qPCR, immunohistochemistry, flow cytometry, microscopy.



Research Opportunities

PhD students, Honours students, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.


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