Metal ion homeostasis in Klebsiella pneumoniae
- Research Opportunity
- PhD, Honours
- Department
- Microbiology and Immunology
- Location
- Doherty Institute
| Primary Supervisor | Number | Webpage | |
|---|---|---|---|
| Associate Professor Christopher McDevitt | christopher.mcdevitt@unimelb.edu.au | (03) 8344 7200 | Personal web page |
| Co-supervisor | Number | Webpage | |
|---|---|---|---|
| Dr Aimee Tan | aitan@unimelb.edu.au | (03) 9035 4473 | Personal web page |
Summary Our recent studies investigating the chemical biology of this bacterium have identified numerous uncharacterised pathways involved in the acquisition of essential metal ion nutrients, such as zinc and molybdenum, from the host. This project will provide the first descriptions of these pathways and how they contribute to the growth, virulence and antibiotic resistance of Klebsiella pneumoniae.
Project Details
Klebsiella pneumoniae is a globally significant multi-drug resistant pathogen. Our recent studies investigating the chemical biology of this bacterium have identified numerous uncharacterised pathways involved in the acquisition of essential metal ion nutrients, such as zinc and molybdenum, from the host. This project will provide the first descriptions of these pathways and how they contribute to the growth, virulence and antibiotic resistance of Klebsiella pneumoniae. The outcomes of this study will provide information essential to exploiting nutrient dependency in breaking multi-drug resistance in Klebsiella pneumoniae and other Gram-negative bacteria.
Faculty Research Themes
School Research Themes
Research Opportunities
PhD, Honours
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
Key Contact
For further information about this research, please contact a supervisor.
Department
Research Group / Unit / Centre
Research Node
Doherty InstituteMDHS Research library
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