Metabolic activity underlying enteric neurons, glia and progenitors

Research Opportunity
PhD, Masters by Research, Honours, Master of Biomedical Science, Post Doctor Research
Department
Anatomy and Neuroscience
Primary Supervisor Email Number Webpage
Dr Marlene Hao hao.m@unimelb.edu.au
Co-supervisor Email Number Webpage
Dr Lincon Stamp lstamp@unimelb.edu.au,

Summary In this study, we will use different transgenic strains of mice and fluorescent activated cell sorting to isolate individual populations of enteric neurons, enteric glia and progenitor cells. We will then analyse the metabolic profile of each population and how they change during development.

Project Details

As progenitor cells differentiate into neurons and glia, there are significant changes to their mode of cellular metabolism, which impacts on their fate potentials. For example, in the central nervous system, neurons primarily rely on oxidative phosphorylation for energy, whilst glial cells rely on glycolysis.

In this study, we will use different transgenic strains of mice and fluorescent activated cell sorting to isolate individual populations of enteric neurons, enteric glia and progenitor cells. We will then analyse the metabolic profile of each population and how they change during development.

Researchers

Dr Lincon Stamp, ARC DECRA Fellow

Dr Marlene Hao, ARC DECRA Fellow

Ms Annette Bergner, Senior Research Assistant

Yvette Wilson, Research Assistant



Faculty Research Themes

Neuroscience

School Research Themes

Biomedical Neuroscience, Stem Cells



Research Opportunities

PhD, Masters by Research, Honours, Master of Biomedical Science, Post Doctor Research
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Anatomy and Neuroscience

Research Group / Unit / Centre

Stamp & Hao laboratory: Development of the enteric nervous system


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