Mapping elemental fluxes during host-pathogen interaction

Research Opportunity
PhD, Honours
Department
Microbiology and Immunology
Location
Doherty Institute
Primary Supervisor Email Number Webpage
Associate Professor Christopher McDevitt christopher.mcdevitt@unimelb.edu.au (03) 8344 7200 Personal web page
Co-supervisor Email Number Webpage
Professor Philip Doble

Summary During infection, the host modulates tissue concentrations of key metal ions (e.g. iron, copper and zinc) to either starve or poison invading bacteria. This project will investigate the temporal and spatial interplay between pathogenic bacteria and the flux of inorganic chemical components at the host-pathogen interface.

Project Details

During infection, the host modulates tissue concentrations of key metal ions (e.g. iron, copper and zinc) to either starve or poison invading bacteria. This project will investigate the temporal and spatial interplay between pathogenic bacteria and the flux of inorganic chemical components at the host-pathogen interface. This will be achieved using an innovative new approach called elemental bio-imaging that allows us to quantitatively map the distribution of metal ions within host organs during infection. This study will provide new insights into how the host manipulates metal ion concentrations to resist bacterial infection.



Faculty Research Themes

Infection and Immunology

School Research Themes

Infection & Immunity



Research Opportunities

PhD, Honours
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Microbiology and Immunology

Research Group / Unit / Centre

McDevitt laboratory

Research Node

Doherty Institute

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