Investigating the role of functional antibodies against Mycobacterium tuberculosis

Research Opportunity
PhD, Masters by Research
Department
Microbiology and Immunology
Location
Doherty Institute
Primary Supervisor Email Number Webpage
Dr Amy Chung awchung@unimelb.edu.au (03) 8344 9938 Personal web page
Co-supervisor Email Number Webpage
Professor Stephen Kent skent@unimelb.edu.au (03) 8344 9939 Personal web page

Summary Preliminary studies by our lab suggest that patients that can control Mycobacterium tuberculosis (Mtb) (latently infected) have improved functional antibody responses compared to symptomatic (active) Mtb patients. Therefore, we are interested in characterising the antibodies from patients with different clinical Mtb disease outcomes in order to further understand the importance of these potentially protective antibodies.

Project Details

Mycobacterium tuberculosis (Mtb) infects approximately one third of the world’s population and is currently one of the major causes of morbidity and death worldwide. The role of antibodies in Mtb is underexplored, although rare studies suggest that antibodies may contribute to Mtb control. Preliminary studies by our lab suggest that patients that can control Mtb (latently infected) have improved functional antibody responses compared to symptomatic (active) Mtb patients. Therefore, we are interested in characterising the antibodies from patients with different clinical Mtb disease outcomes in order to further understand the importance of these potentially protective antibodies.



Faculty Research Themes

Infection and Immunology

School Research Themes

Infection & Immunity



Research Opportunities

PhD, Masters by Research
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Microbiology and Immunology

Research Node

Doherty Institute

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