Investigating cocaine and amphetamine regulated transcript (CART) in binge drinking

Research Opportunity
PhD students, Honours students, Master of Biomedical Science
Number of Honour Places Available
Number of Master Places Available
Primary Supervisor Email Number Webpage
Dr Leigh Walker
Co-supervisor Email Number Webpage
Prof Andrew Lawrence

Summary The Addiction Neuroscience Laboratory at Florey Institute of Neuroscience and Mental Health. Our overarching research aim is to understand the brain mechanisms that drive drug and alcohol-seeking, and relapse to drug-seeking after a period of abstinence. We are also interested in the effects of chronic drug and alcohol intake on cognition and behaviour. Our lab employs a range of different behavioural and molecular techniques to investigate cellular and circuitry changes that occur as a result of exposure to drugs and alcohol, and how these changes may lead to the compulsive behaviour that is characteristic of addiction.

Project Details

Alcohol is the leading cause of death globally of people aged 15-49 and is a major socioeconomic burden on Australian society. Alcohol use disorders are an emerging issue in females with rates increasing over 80% in the last 15 years. Current therapeutics fail to adequately address this problem, and sex differences remain understudied. We have recently implicated sex dependent role for the neuropeptide, cocaine and amphetamine regulated transcript (CART) in binge alcohol consumption. However, the regions in which this neuropeptide acts to mediate these behaviours require elucidation.

Research Opportunities

PhD students, Honours students, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

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