Integrative infectious disease phylodynamics

Research Opportunity
PhD
Department
Microbiology and Immunology
Location
Doherty Institute
Primary Supervisor Email Number Webpage
Dr Sebastian Duchene sebastian.duchene@unimelb.edu.au 8344 3971 Personal web page
Co-supervisor Email Number Webpage
Dr Mark Dvaies mark.davies1@unimelb.edu.au (03) 9035 6519 Personal web page

Summary This project has two broad aims; (i) to develop Bayesian hierarchical models to integrate different types of data, and (ii) to leverage these models for real-time genome surveillance where computational speed is essential. This project has a strong methodological component, but it will capitalise on public health genome data. An understanding of phylogenetics, Bayesian statistics, and programming skills in one scripting language (e.g. R or Python) is essential.

Project Details

Recent advances in sequencing technologies have increased the amount of genome data available for many organisms. As microbial pathogens evolve very rapidly, such genome data are informative about their transmission dynamics, a field known phylodynamics. A key challenge in phylodynamics is coupling genome sequence data with other sources of information (e.g. epidemiology, drug resistance, and geographic location).

This project has two broad aims;

  1. to develop Bayesian hierarchical models to integrate different types of data, and
  2. to leverage these models for real-time genome surveillance where computational speed is essential.

This project has a strong methodological component, but it will capitalise on public health genome data. An understanding of phylogenetics, Bayesian statistics, and programming skills in one scripting language (e.g. R or Python) is essential. There are opportunities for a PhD stipend or top-up for highly motivated candidates.



Faculty Research Themes

Infection and Immunology

School Research Themes

Infection & Immunity



Research Opportunities

PhD
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Microbiology and Immunology

Research Node

Doherty Institute

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