How does ageing effect antibody responses?
- Research Opportunity
- Masters by Research, Honours
- Department
- Microbiology and Immunology
- Location
- Doherty Institute
| Primary Supervisor | Number | Webpage | |
|---|---|---|---|
| Dr Amy Chung | awchung@unimelb.edu.au | (03) 8344 9938 | Personal web page |
| Co-supervisor | Number | Webpage | |
|---|---|---|---|
| Dr Nichollas Scott | nichollas.scott@unimelb.edu.au | (03) 8344 6724 | Personal web page |
| Professor Stephen Kent | skent@unimelb.edu.au | (03) 8344 9939 | Personal web page |
Summary This project aims to further understand the effect of ageing upon antibody responses using non-human primate models.
Project Details
Antibodies are a vital component of the immune response required for protection and control of infectious diseases. However, large changes can occur to the quality of an antibody response as a person grows older. One of the reasons for this change is glycosylation, where sugar structures are added to the antibody. Different glycan structures can determine how well the antibody activates surrounding innate immune cells to attack and eliminate invading pathogens. Intriguingly, within humans, large antibody glycan changes are observed within infants and elderly, which may contribute to why they are more susceptible to infection. This project aims to further understand the effect of ageing upon antibody responses using non-human primate models.
Faculty Research Themes
School Research Themes
Research Opportunities
Masters by Research, Honours
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
Key Contact
For further information about this research, please contact a supervisor.
Department
Research Node
Doherty InstituteMDHS Research library
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