How do tumours impact normal tissue functions?
- Research Opportunity
- PhD, Masters by Research, Honours
- Department
- Microbiology and Immunology
- Location
- Doherty Institute
| Primary Supervisor | Number | Webpage | |
|---|---|---|---|
| Associate Professor Scott Mueller | smue@unimelb.edu.au | (03) 8344 9044 | Personal web page |
| Co-supervisor | Number | Webpage | |
|---|---|---|---|
| Dr Yannick Alexandre | yannick.alexandre@unimelb.edu.au | 8344 0815 |
Summary This project will examine the bi-directional interactions between tumour cells and stromal cells in the lymphoid organs, in order to define how cancer impacts tissue functions, and identify mechanisms to restrict tumour growth and improve disease outcomes.
Project Details
Cancer cells hijack local tissue environments to support their growth, survival and metastasis. Stromal cells such as fibroblasts form critical supportive networks in tissues and express key molecules that influence tumour growth. The overall impact of tumours on the functions of stromal cells within tissues is poorly understood. This project will examine the bi-directional interactions between tumour cells and stromal cells in the lymphoid organs, in order to define how cancer impacts tissue functions, and identify mechanisms to restrict tumour growth and improve disease outcomes. Advanced multi-colour imaging, flow cytometry and molecular techniques will be used in this project.
Faculty Research Themes
School Research Themes
Research Opportunities
PhD, Masters by Research, Honours
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
Key Contact
For further information about this research, please contact a supervisor.
Department
Research Group / Unit / Centre
Mueller laboratory: Visualising the immune system in action
Research Node
Doherty InstituteMDHS Research library
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