How do tumours impact normal tissue functions?

Research Opportunity
PhD, Masters by Research, Honours
Department
Microbiology and Immunology
Location
Doherty Institute
Primary Supervisor Email Number Webpage
Associate Professor Scott Mueller smue@unimelb.edu.au (03) 8344 9044 Personal web page
Co-supervisor Email Number Webpage
Dr Yannick Alexandre yannick.alexandre@unimelb.edu.au 8344 0815

Summary This project will examine the bi-directional interactions between tumour cells and stromal cells in the lymphoid organs, in order to define how cancer impacts tissue functions, and identify mechanisms to restrict tumour growth and improve disease outcomes.

Project Details

Cancer cells hijack local tissue environments to support their growth, survival and metastasis. Stromal cells such as fibroblasts form critical supportive networks in tissues and express key molecules that influence tumour growth. The overall impact of tumours on the functions of stromal cells within tissues is poorly understood. This project will examine the bi-directional interactions between tumour cells and stromal cells in the lymphoid organs, in order to define how cancer impacts tissue functions, and identify mechanisms to restrict tumour growth and improve disease outcomes. Advanced multi-colour imaging, flow cytometry and molecular techniques will be used in this project.



Faculty Research Themes

Infection and Immunology

School Research Themes

Infection & Immunity



Research Opportunities

PhD, Masters by Research, Honours
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Microbiology and Immunology

Research Group / Unit / Centre

Mueller laboratory: Visualising the immune system in action

Research Node

Doherty Institute

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