Determining the role of diet and microbiota in the progression of lupus
- Research Opportunity
- PhD, Masters by Research, Honours
- Microbiology and Immunology
- Doherty Institute
|Professor Fabienne Mackayfirstname.lastname@example.org||(03) 8344 2726||Personal web page|
|Dr William Figgettemail@example.com||(03) 8344 1589||Personal web page|
|Dr Catherine Kennedyfirstname.lastname@example.org||(03) 9035 8195||Personal web page|
Summary The role of the gut microbiome and the potential for diet-based therapies in Systemic Lupus Erythematosus (SLE) and their mechanisms of protection will be studied in this project, using SLE-prone mouse models, incorporating advanced methods of metabolomics and microbial metagenomics profiling.
Systemic Lupus Erythematosus (SLE) is a debilitating autoimmune disease driven by aberrant B cells producing antibodies against self. This leads to inflammation and ultimately tissue destruction. Today we have no cure for SLE and the current treatments are symptom-focused. Recent advancements in the understanding of the importance of diet and gut microbiota point to a potential role for dietary intervention in the treatment of various autoinflammatory diseases. The role of the gut microbiome and the potential for diet-based therapies in SLE and their mechanisms of protection will be studied in this project, using SLE-prone mouse models, incorporating advanced methods of metabolomics and microbial metagenomics profiling.
Faculty Research Themes
School Research Themes
PhD, Masters by Research, Honours
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
For further information about this research, please contact a supervisor.
Research Group / Unit / Centre
Research NodeDoherty Institute
MDHS Research library
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