Application of systems genomics to analysing the dynamics of Streptococcus pyogenes infection

Research Opportunity
PhD, Honours
Department
Microbiology and Immunology
Location
Doherty Institute
Primary Supervisor Email Number Webpage
Dr Mark Davies mark.davies1@unimelb.edu.au (03) 9035 6519 Personal web page

Summary This project will examine the systems biology of Streptococcus pyogenes subjected to a major and important stress, transition from the ex vivo environment to blood. The research will use various aspects of molecular biology and especially bioinformatics to address the key research questions.

Project Details

The relationship between, and integration of, genomics, transcriptomics, proteomics and metabolomics lies at the heart of understanding how organisms, including bacteria, respond to environmental changes and especially stress, be it physical, immunological or nutritional. This is generically termed systems biology. This project will examine the systems biology of Streptococcus pyogenes subjected to a major and important stress, transition from the ex vivo environment to blood. The research will use various aspects of molecular biology and especially bioinformatics to address the key research questions. Avenues are available to expand this research into looking at immunogenetics within a controlled human infection model.



Faculty Research Themes

Infection and Immunology

School Research Themes

Infection & Immunity



Research Opportunities

PhD, Honours
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Microbiology and Immunology

Research Node

Doherty Institute

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