Biomedical Sciences Projects by Department

Biomedical Sciences Projects by Department

Anatomy and Neuroscience

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Projects Primary Supervisor Department Research Themes Research Opportunity
A gut feeling about new therapies for glioma treatment Doctor Marlene Hao
 Anatomy and Neuroscience Stem Cells PhD, Masters by Research, Honours, Master of Biomedical Science, Post Doctor Research
Can drug-like mimetics of BDNF promote remyelination after injury? Dr Junhua Xiao
 Anatomy and Neuroscience Molecular Mechanisms of Disease,Therapeutics and Translation PhD, Masters by Research, Honours, Master of Biomedical Science
Dental morphology Dr Varsha Pilbrow
 Anatomy and Neuroscience Cellular Imaging and Structural Biology PhD, Masters by Research, Honours, Master of Biomedical Science
Genes underlying differentiation of enteric neuronal subtypes Dr Lincon Stamp
 Anatomy and Neuroscience Stem Cells PhD, Masters by Research, Honours, Master of Biomedical Science, Post Doctor Research
How do dietary nutrients affect the ability of stem cells and stem cell-derived tumours to grow and divide? Dr Louise Cheng
 Anatomy and Neuroscience Stem Cells PhD, Masters by Research, Honours
How do neurons maintain their specialised status? Dr Louise Cheng
 Anatomy and Neuroscience Stem Cells,Cancer in Biomedicine PhD, Masters by Research, Honours
How do tumours compete with other tissues for resources? Dr Louise Cheng
 Anatomy and Neuroscience Stem Cells,Cancer in Biomedicine PhD, Masters by Research, Honours
How early life experience influences brain myelination and function late in life? Dr Junhua Xiao
 Anatomy and Neuroscience Molecular Mechanisms of Disease,Therapeutics and Translation PhD, Masters by Research, Honours, Master of Biomedical Science
Investigating the molecular basis of central myelination and repair Dr Junhua Xiao
 Anatomy and Neuroscience Molecular Mechanisms of Disease,Therapeutics and Translation PhD, Masters by Research, Honours, Master of Biomedical Science
Metabolic activity underlying enteric neurons, glia and progenitors Dr Marlene Hao
 Anatomy and Neuroscience Stem Cells PhD, Masters by Research, Honours, Master of Biomedical Science, Post Doctor Research
Mummy Studies Dr Varsha Pilbrow
 Anatomy and Neuroscience Cellular Imaging and Structural Biology PhD, Masters by Research, Honours, Master of Biomedical Science
Potential of stem cell therapy to treat Hirschsprung’s disease Dr Lincon Stamp
 Anatomy and Neuroscience Stem Cells PhD, Masters by Research, Honours, Master of Biomedical Science, Post Doctor Research
Principles of Peripheral Nerve Myelination Dr Simon Murray
 Anatomy and Neuroscience Molecular Mechanisms of Disease,Therapeutics and Translation PhD, Masters by Research, Honours, Master of Biomedical Science
Skeletal morphology Dr Varsha Pilbrow
 Anatomy and Neuroscience Cellular Imaging and Structural Biology PhD, Masters by Research, Honours, Master of Biomedical Science
Understanding interactions between gut epithelial stem cells and enteric neurons Dr Lincon Stamp
 Anatomy and Neuroscience Stem Cells PhD, Masters by Research, Honours, Master of Biomedical Science, Post Doctor Research

Biochemistry and Molecular Biology

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Projects Primary Supervisor Department Research Themes Research Opportunity
A novel link between metabolism and host defence: O-GlcNAc glycosylation Professor Jose Villadangos
 Biochemistry and Molecular Biology Cancer in Biomedicine,Molecular Mechanisms of Disease PhD, Masters by Research, Honours, Master of Biomedical Science
Analysing protein structures Dr David Ascher
 Biochemistry and Molecular Biology Molecular Mechanisms of Disease PhD, Masters by Research, Honours, Master of Biomedical Science
Characterisation of the changes of the endocytic and secretory pathway of dendritic cells upon activation Associate Professor Isabelle Rouiller
 Biochemistry and Molecular Biology Masters by Research, Honours, Master of Biomedical Science
Decoding the trafficking of immune receptors Dr Justine Mintern
 Biochemistry and Molecular Biology Cancer in Biomedicine,Cell Signalling,Molecular Mechanisms of Disease PhD, Honours, Master of Biomedical Science
Designing better drugs Dr David Ascher
 Biochemistry and Molecular Biology PhD, Masters by Research, Honours, Master of Biomedical Science
Designing new optogenetic tools for biomedical research A/Prof Danny Hatters
 Biochemistry and Molecular Biology Cell Signalling PhD, Masters by Research, Honours
Development of Novel antimalarial drugs Professor Leann Tilley
 Biochemistry and Molecular Biology Therapeutics and Translation PhD, Masters by Research, Honours
Exploiting nanoparticles as vaccines Dr Justine Mintern
 Biochemistry and Molecular Biology Cancer in Biomedicine,Cell Signalling,Molecular Mechanisms of Disease PhD, Honours, Master of Biomedical Science
Finding clarity within a blizzard- guiding the solution of cryo-EM structures Dr David Ascher
 Biochemistry and Molecular Biology PhD, Masters by Research, Honours, Master of Biomedical Science
Immunoregulatory functions of the MARCH family of ubiquitin ligases Professor Jose Villadangos
 Biochemistry and Molecular Biology Cancer in Biomedicine,Molecular Mechanisms of Disease PhD, Masters by Research, Honours, Master of Biomedical Science
Improving the diagnostic outcomes of patients with mitochondrial disease Dr David Stroud
 Biochemistry and Molecular Biology Systems Biology,Molecular Mechanisms of Disease,Cardio-Respiratory PhD, Masters by Research, Honours, Master of Biomedical Science
Investigating mechanisms of protein trafficking to human mitochondria Dr Diana Stojanovski
 Biochemistry and Molecular Biology Molecular Mechanisms of Disease,Systems Biology PhD, Masters by Research, Honours
Malaria parasite-infected red blood cells: a renovator’s dream Professor Leann Tilley
 Biochemistry and Molecular Biology Cellular Imaging and Structural Biology PhD, Masters by Research, Honours
Manipulating immunity to fight infection and tumours Dr Justine Mintern
 Biochemistry and Molecular Biology Cancer in Biomedicine,Molecular Mechanisms of Disease PhD, Honours, Master of Biomedical Science
Mapping the proteome vulnerable to unfolding and aggregation under proteostasis stress A/Prof Danny Hatters
 Biochemistry and Molecular Biology Molecular Mechanisms of Disease PhD, Masters by Research, Honours
Personalising treatments for genetic diseases Dr David Ascher
 Biochemistry and Molecular Biology Molecular Mechanisms of Disease PhD, Masters by Research, Honours, Master of Biomedical Science
Protein trafficking and cellular architecture Professor Leann Tilley
 Biochemistry and Molecular Biology Cellular Imaging and Structural Biology PhD, Masters by Research, Honours
Rational Protein Engineering Dr David Ascher
 Biochemistry and Molecular Biology PhD, Masters by Research, Honours, Master of Biomedical Science
Sex in human malaria parasites Dr Matthew Dixon
 Biochemistry and Molecular Biology Molecular Mechanisms of Disease PhD, Masters by Research, Honours, Master of Biomedical Science
Small molecules for BIG targets- Targeting protein-protein interactions with fragments Dr David Ascher
 Biochemistry and Molecular Biology Systems Biology,Molecular Mechanisms of Disease PhD, Masters by Research, Honours, Master of Biomedical Science
Solving the native structure of the malaria parasite using cryo-electron microscopy Professor Leann Tilley
 Biochemistry and Molecular Biology Cellular Imaging and Structural Biology PhD, Masters by Research, Honours
Structural Biology of Cancer Professor Michael Parker
 Biochemistry and Molecular Biology Cancer in Biomedicine,Cell Signalling,Molecular Mechanisms of Disease PhD, Honours
Structural Biology of Infection Professor Michael Parker
 Biochemistry and Molecular Biology Molecular Mechanisms of Disease PhD, Honours
Structural Neurobiology Professor Michael Parker
 Biochemistry and Molecular Biology Cell Signalling,Molecular Mechanisms of Disease PhD, Honours
Tackling drug resistance Dr David Ascher
 Biochemistry and Molecular Biology Molecular Mechanisms of Disease PhD, Masters by Research, Honours, Master of Biomedical Science
The amyloidogenic protease inhibitor Cystatin C in health and disease Prof. Jose Villadangos
 Biochemistry and Molecular Biology Cardio-Respiratory,Molecular Mechanisms of Disease PhD, Masters by Research, Honours, Master of Biomedical Science
The role of mitochondria in Coxiella burnetii infection Dr Diana Stojanovski
 Biochemistry and Molecular Biology Molecular Mechanisms of Disease PhD, Masters by Research, Honours
Treating the person not the disease Dr David Ascher
 Biochemistry and Molecular Biology Molecular Mechanisms of Disease,Systems Biology PhD, Masters by Research, Honours, Master of Biomedical Science
Understanding how Anthrax toxins function Associate Professor Isabelle Rouiller
 Biochemistry and Molecular Biology Molecular Mechanisms of Disease PhD, Masters by Research
Understanding how membrane-less organelles form with optogenetic tools A/Prof Danny Hatters
 Biochemistry and Molecular Biology Molecular Mechanisms of Disease PhD, Masters by Research, Honours
Understanding how the ATPase p97 functions at molecular level Associate Professor Isabelle Rouiller
 Biochemistry and Molecular Biology Molecular Mechanisms of Disease PhD, Masters by Research, Honours, Master of Biomedical Science
Understanding immune dysfunction in acute myeloid leukemia Dr Justine Mintern
 Biochemistry and Molecular Biology Cell Signalling,Cancer in Biomedicine,Molecular Mechanisms of Disease PhD, Honours, Master of Biomedical Science
Understanding the assembly of mitochondrial machines Dr David Stroud
 Biochemistry and Molecular Biology Cardio-Respiratory,Molecular Mechanisms of Disease,Systems Biology PhD, Masters by Research, Honours, Master of Biomedical Science
Understanding the Molecular Consequences of Mutations Dr David Ascher David Ascher
 Biochemistry and Molecular Biology Molecular Mechanisms of Disease PhD, Masters by Research, Honours, Master of Biomedical Science
Using the immune system to kill tumours Dr Justine Mintern
 Biochemistry and Molecular Biology Cancer in Biomedicine,Cell Signalling,Molecular Mechanisms of Disease PhD, Honours, Master of Biomedical Science

Microbiology and Immunology

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Projects Primary Supervisor Department Research Themes Research Opportunity
A cell-based model of sporadic prion disease Associate Professor Vicki Lawson
 Microbiology and Immunology Infection and Immunity Masters by Research, Honours
Age-dependent susceptibility of neurons to RNA virus infection Dr Lukasz Kedzierski
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Application of systems genomics to analysing the dynamics of Streptococcus pyogenes infection Dr Mark Davies
 Microbiology and Immunology Infection and Immunity PhD, Honours
Are there additional MAIT cell antigens? Dr Sidonia Eckle
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Blocking the development of secondary bacterial pneumonia Dr Linda Wakim
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Can resident memory B cells in the lung protect against respiratory syncytial virus? Professor Stephen Kent
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research
CCVs: Clathrin-coated vesicles and Coxiella containing vacuoles Dr Hayley Newton
 Microbiology and Immunology Infection and Immunity PhD, Honours
Characterisation of antimicrobial resistance and virulence of novel staphylococcal lineages Associate Professor Steven Tong
 Microbiology and Immunology Infection and Immunity PhD, Honours
Defining the association between virulence and fitness of seasonal influenza viruses Professor Kanta Subbarao
 Microbiology and Immunology Infection and Immunity PhD
Determining the role of diet and microbiota in the progression of lupus Professor Fabienne Mackay
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Development of novel proteomic tools to explore Burkholderia pathogenesis Dr Nichollas Scott
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Diagnosis, treatment and prevention of medically relevant prion diseases Associate Professor Vicki Lawson
 Microbiology and Immunology Infection and Immunity Masters by Research, Honours
Discovery of malaria vaccine peptide targets Dr Daniel Fernandez-Ruiz
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Evolution of streptococcal pathovars Dr Mark Davies
 Microbiology and Immunology Infection and Immunity PhD, Honours
Evolutionary Genetics of avian influenza A viruses in Australia Dr Michelle Wille
 Microbiology and Immunology Infection and Immunity Honours
Gamma delta T cells are important for malaria sporozoite vaccination Dr Lynette Beattie
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Harnessing the molecular clock to activate diverse strains of latent HIV Professor Sharon Lewin
 Microbiology and Immunology Infection and Immunity Honours
How do tumours impact normal tissue functions? Associate Professor Scott Mueller
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
How does ageing effect antibody responses? Dr Amy Chung
 Microbiology and Immunology Infection and Immunity Masters by Research, Honours
How infection and trauma cause dendritic cell paralysis and lethal immunosuppression Professor Jose Villadangos
 Microbiology and Immunology Cancer in Biomedicine,Molecular Mechanisms of Disease PhD, Masters by Research, Honours, Master of Biomedical Science
How is selective metal ion transport achieved at the host-pathogen interface? Associate Professor Christopher McDevitt
 Microbiology and Immunology Infection and Immunity PhD, Honours
How to harness the immune system to cure cancer: adoptive cell immunotherapy Professor Jose Villadangos
 Microbiology and Immunology Cancer in Biomedicine PhD, Masters by Research, Honours, Master of Biomedical Science
Identification and characterisation of novel malarial transmission-blocking antigens Associate Professor Siddhartha Mahanty
 Microbiology and Immunology Infection and Immunity Masters by Research, Honours
Identifying novel subsets of immune cells that control cytomegalovirus following transplantation Dr Lucy Sullivan
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Immuno-paralysis following severe infections or trauma Professor Jose Villadangos
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Immunoregulatory functions of the MARCH family of ubiquitin ligases Professor Jose Villadangos
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Infection induced changes to splenic macrophages Dr Lynette Beattie
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Integrative infectious disease phylodynamics Dr Sebastian Duchene
 Microbiology and Immunology Infection and Immunity PhD
Interrogating B cell immunity to influenza vaccines Professor Stephen Kent
 Microbiology and Immunology PhD, Masters by Research
Investigating the effect of hepatitis B virus splice variants in liver cells and disease progression Professor Peter Revill
 Microbiology and Immunology Infection and Immunity Honours
Investigating the role of functional antibodies against Mycobacterium tuberculosis Dr Amy Chung
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research
Location, location, location – lodging virus specific T cells in the lung as an approach to protecting against influenza virus infection Dr Linda Wakim
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research
Manipulating MAIT cells for increased protection by vaccination and therapy Dr Alexandra Corbett
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Mapping elemental fluxes during host-pathogen interaction Associate Professor Christopher McDevitt
 Microbiology and Immunology Infection and Immunity PhD, Honours
Metal ion homeostasis in Klebsiella pneumoniae Associate Professor Christopher McDevitt
 Microbiology and Immunology Infection and Immunity PhD, Honours
Mitochondria and intracellular bacterial pathogens Dr Hayley Newton
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Molecular basis for growth factor surveillance in natural killer cells Dr Alexander David Barrow
 Microbiology and Immunology PhD, Masters by Research, Honours
Molecular basis for growth factor surveillance in plasmacytoid dendritic cells Dr Alexander David Barrow
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
MR1 – a molecular alarm system for bacterial infection Dr Hamish McWilliam
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
MR1 – a molecular alarm system that detects pathogen metabolites Professor Jose Villadangos
 Microbiology and Immunology Cancer in Biomedicine,Molecular Mechanisms of Disease PhD, Masters by Research, Honours, Master of Biomedical Science
Neural regulation of anti-cancer immunity Associate Professor Scott Mueller
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Neurodegeneration in the enteric nervous system Associate Professor Vicki Lawson
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Novel master-regulators of B-cell biology Professor Fabienne Mackay
 Microbiology and Immunology Infection and Immunity Masters by Research, Honours
Pathogenesis of pneumococcal pneumonia Associate Professor Catherine Satzke
 Microbiology and Immunology Infection and Immunity Masters by Research, Honours
Population genomics of endemic Streptococcus pyogenes Dr Mark Davies
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Preventing infections of the highly puke-ogenic virus - norovirus Professor Jason Mackenzie
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Programming gamma delta T cells for HIV immunotherapy Professor Stephen Kent
 Microbiology and Immunology Infection and Immunity Masters by Research, Honours
Protective capacity of malaria-specific liver-tissue-resident memory T cells Dr Lauren Holz
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Quantifying bacterial recombination within globally evolving streptococcal pathogens Dr Mark Davies
 Microbiology and Immunology Infection and Immunity PhD, Honours
Regeneration of lymphoid tissues Associate Professor Scot Mueller
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Role of O-linked glycosylation system across the Burkholderia genus Dr Nichollas Scott
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Role of suppressor of cytokine signalling proteins in viral encephalitis Dr Lukasz Kedzierski
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
SNAP - Staphylococcus aureus Network Adaptive Platform Trial Associate Professor Steven Tong
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Staphylococcus aureus bloodstream infections in Victorian hospitals: regional differences in disease burden and epidemiology Associate Professor Leon Worth
 Microbiology and Immunology Infection and Immunity Masters by Research, Honours
Streptococcal transmission and disease Associate Professor Catherine Satzke
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Synergistic and antagonistic interplay between Streptococcus pneumoniae and respiratory viruses Associate Professor Catherine Satzke
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Testing a novel strategy to target chronic lymphocytic leukemia Professor Fabienne Mackay
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
The importance of IgA in the protection and control of infectious diseases Dr Amy Chung
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research
The role of co-pathologies in the clinical presentation of prion disease Associate Professor Vicki Lawson
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
The role of glucose metabolism in the regulation of immunity Professor Jose Villadangos
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
The role of the prion protein in brain cancer Associate Professor Vicki Lawson
 Microbiology and Immunology Infection and Immunity Masters by Research, Honours
The space of evolutionary trees in infectious disease epidemiology Dr Sebastian Duchene
 Microbiology and Immunology Infection and Immunity Masters by Research, Honours
Understanding the biological chemistry of pneumococcal disease Associate Professor Christopher McDevitt
 Microbiology and Immunology Infection and Immunity PhD, Honours
Understanding the immune microenvironment in brain tumours Dr Theo Mantamadiotis
 Microbiology and Immunology Cancer in Biomedicine,Infection and Immunity PhD, Masters by Research, Honours
Understanding the importance of variation in the capsular polysaccharide of Streptococcus pneumoniae Associate Professor Catherine Satzke
 Microbiology and Immunology Infection and Immunity Masters by Research, Honours
Understanding the mechanisms that impair anti-tumour adoptive cell therapy Professor Jose Villadangos
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Understanding the role of MAIT cells in immune-mediated pathology Dr Sidonia Eckle
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Understanding the role of MAIT cells in protection from microbial infections Dr Sidonia Eckle
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Unravelling the drivers of scarlet fever pandemics Dr Mark Davies
 Microbiology and Immunology Infection and Immunity PhD, Honours
Using genomics to investigate the transmission of skin pathogens and antimicrobial resistance in a ‘One Health’ setting Dr Mark Davies
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Using transcriptional analyses to understand recognition of tumours by natural killer cells Professor Andrew Brooks
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Validating human transgenic mouse models for lupus therapeutics development Professor Fabienne Mackay
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
Vertical transmission of Ross River virus in mosquito vectors Dr Julio Rodriguez-Andres
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours
What do antibodies need to do to protect a woman against pregnancy-malaria? Dr Elizabeth Aitken
 Microbiology and Immunology Infection and Immunity Honours
Whole body analysis of human tissue-resident memory T cells Dr Claire Gordon
 Microbiology and Immunology Infection and Immunity PhD
Why is the flavivirus RdRp in the nucleus? Professor Jason Mackenzie
 Microbiology and Immunology Infection and Immunity PhD, Masters by Research, Honours

Pharmacology and Therapeutics

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Projects Primary Supervisor Department Research Themes Research Opportunity
Development and application of soft culturing microenvironment for novel drug discovery Professor Alastair Stewart
 Pharmacology and Therapeutics Masters by Research, Honours, Master of Biomedical Science
Glucocorticoid responsiveness in the lung: impact of inflammation and infection Professor Alastair Stewart
 Pharmacology and Therapeutics Masters by Research, Honours, Master of Biomedical Science
Manipulating the endocannabinoid system to alter cardiovascular function in hypertension Dr Makhala Khammy
 Pharmacology and Therapeutics Cardio-Respiratory PhD, Masters by Research, Honours, Master of Biomedical Science
“Clock-off time” for inflammation and remodelling in chronic inflammatory diseases: casein kinase inhibitors Professor Alastair Stewart
 Pharmacology and Therapeutics Molecular Mechanisms of Disease Masters by Research, Honours, Master of Biomedical Science

Physiology

No research opportunities are currently being offered within this department