Gastrointestinal Cancer Research Group

Led by Professor Alex Boussioutas
Department of Medicine and Radiology
alexb@unimelb.edu.au
+61 3 8345 6816

Alex's lab focuses on: 

- understanding premalignant stages of disease (intestinal metaplasia) and how they progress to cancer to allow prevention strategies;
- tumour microenvironment and how this influences outcomes of disease in gastric cancer; and
- biomarkers and precision medicine, to enable discovery of biomarkers for screening and early detection of cancer.

Alex's research team investigates translational aspects of gastrointestinal oncology. Research disciplines span population health and epidemiology of gastric and colorectal cancer, integrative genomic analysis of gastric and oesophageal cancer, cell biology of invasion and metastasis with respect to the tumour microenvironment, early detection and biomarkers of gastric cancer and genetic aspects of gastrointestinal malignancies.

The team is currently engaged in a number of research areas, mainly in understanding cellular and molecular aspects of upper gastrointestinal cancers like gastric cancer and oesophageal adenocarcinoma. Alex also has an interest in screening and prevention of colorectal cancer, particularly in high risk populations, such as those with hereditary predisposition.