The Dunstan Group is using host and pathogen genomics to better understand infectious diseases. They perform genome-wide association studies of the host, genomic studies of the pathogen, and investigate the interaction of both genomes in tuberculosis, enteric fever and malaria patients.
The focus of the Mahanty group's research is on the pathogenesis and immunology of malaria. The goal of their research studies is to elucidate the mechanisms underlying the clinical severity of illness caused by human infections with Plasmodium falciparum, the parasite responsible for the majority of cases of severe malaria, and to better understand protective immune mechanism in the human host.
Jodie McVernon’s group uses established and emerging biostatistical, epidemiologic and modelling methods to address infectious diseases questions of public health relevance. We bring a suite of collaborators from animal health and ecology to provide a ‘One Health’ perspective on emerging human pathogens.
Stinear Group research addresses priorities across four connected themes that including hospital superbugs, pathogenic mycobacteria, natural product discovery and public health genomics that aim to understand and contain the spread of bacteria causing serious human disease.
The Lewin Group
The main focus of the Lewin group is to understand why HIV infection persists on antiretroviral therapy, to develop new strategies to eliminate latency and to define the biological determinants of immune reconstitution and factors that drive liver disease in HIV-hepatitis B virus co-infection.
The Tong Group conducts clinical trials to optimise the treatment of infections due to methicillin-resistant Staphylococcus aureus and other bacterial pathogens. It investigates the epidemiology and genomics of streptococcal infections, hepatitis B, influenza, and antimicrobial resistance in Australian Indigenous communities.
Elizabeth’s group investigates novel ways to block cancer growth with a focus on the gastrointestinal tract – stomach, bowel and liver. A cell-cell communication pathway called Wnt is hyperactive in these cancers. Their research shows inhibiting Wnt has potent anti-cancer effects.
Vaccine and Immunisation Research Group (VIRGo)
The Vaccine & Immunisation Research Group (VIRGo) led by Terry Nolan conducts research that advises policy makers on the optimal use of vaccines in national immunisation schedules, and in pandemic preparedness and response. VIRGo has completed industry and investigator-initiated clinical trials whose findings have been vital for the licensure of several vaccines now in use throughout the world.