Moseley laboratory: Viral pathogenesis
Viruses pose one of the grand challenges to human and animal health globally and within Australia. Viral disease progression is critically dependent on the formation of specific interaction networks between viral proteins and host cell factors, which enable viral subversion of important processes such as antiviral immunity and cell survival.
Research in the Moseley laboratory seeks to elucidate these interactions at the molecular level and to understand their functions in diseases caused by highly lethal human viruses, including rhabdoviruses (e.g. rabies virus, Australian bat lyssavirus), paramyxoviruses (e.g. Nipah, Hendra, measles) and filoviruses (e.g. Ebola), as well as a number of agriculturally significant and potentially zoonotic animal viruses.
The overarching aim of the research is to identify novel targets and strategies for the development of new vaccines and therapeutics for currently incurable viral diseases.
Our research involves extensive collaborations within the University of Melbourne, and with other leading national (e.g. CSIRO-AAHL, Monash University and MIMR, University of Sydney) and international institutes (e.g. The Pasteur Institute and CNRS, Paris; Gifu and Hokkaido Universities, Japan; Universities of Dundee and St. Andrews (UK), enabling access to unique resources and technologies including novel and highly pathogenic viruses.
Research staff Stephen Rawlinson, Postdoctoral Fellow
Kim Gia Lieu, Postdoctoral Fellow
Cassandra David, Research Assistant Graduate students Aaron Brice, PhD Student
Angela Harrison, PhD Student
Divya Narayanan, PhD Student
Caitlin Rowe, PhD Student
Mengxiao Luo, PhD Student
Click here for the results of a PubMed search of Greg's publications.
Click here for the results of a Google Scholar analysis of Greg's publications.
- Viral interactions with the cytoskeleton in the manipulation of host cell biology
- Virus-STAT interactions: Roles in disease and therapeutic targeting
- Characterisation of immune evasion mechanisms in novel and emerging viruses
- The roles of intranuclear viral protein interactions in disease
Faculty Research Themes
School Research Themes
For further information about this research, please contact Dr Greg Moseley