Neurodegenerative Diseases

We are currently seeking Senior Research Fellows/ Academic Level C – join us as we strengthen our neurodegenerative disease research program. Apply now.

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Neurodegenerative diseases collectively represent a major health burden. The clinical conditions driven by neurodegeneration are protean and include Alzheimer’s disease, Parkinson's disease, motor neuron disease (MND) and Huntington’s disease, extending to progressive multiple sclerosis, the sequelae of traumatic brain injury and degenerative diseases of the retina. The likelihood of developing neurodegenerative disease increases with advancing age, therefore an ageing global population and increasing life expectancy means that the incidence of neurodegenerative disease is escalating. An unfortunate commonality shared by all neurodegenerative diseases is the absence of effective therapeutics.

The University of Melbourne and its partners are at the forefront of neurodegenerative disease research. This requires multidisciplinary methods to understand the development of disease and disease mechanisms including genomics, transcriptomics, proteomics, molecular and cell biology, state of the art structural and molecular imaging technologies and medicinal chemistry. Key research areas include the development of effective therapeutics for clinical trial; the study of impaired energy metabolism in neuronal failure; the discovery of novel programmed cell death pathways such as ferroptosis; protein misfolding and aggregation; the role of the innate immune system in modulating disease outcome. Research also extends to transmissible neurodegeneration caused by prion diseases.

The University of Melbourne is seeking new researchers at academic level C who can join in and benefit from our developing critical mass of research talent and facilities for neurodegenerative disease research. We are seeking researchers with demonstrated expertise to build an internationally competitive research program in:

  • fundamental or translational studies of neurodegenerative disease including clinical trials of potential therapeutics
  • genetic susceptibility, genomics and precision medicine in neurodegenerative disease
  • target identification and validation including neuroproteomics and structural biology
  • neuroimmunology and its role in modulating disease outcome
  • medicinal chemistry and neuropharmaceutical development
  • use of biomarkers including imaging techniques to assist diagnosis and monitoring of disease progression.

Applications are open until 24th July 2018 and will require a:

For enquiries please email: mdhs-campaign@unimelb.edu.au

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Key partners, schools and centres at the University of Melbourne involved in genomics and precision medicine:

School of Biomedical Sciences

Melbourne Dementia Research Centre

Melbourne School of Psychological Sciences

Melbourne Medical School

Melbourne School of Health Sciences

Phoenix Institute

Bio21 Molecular Science & Biotechnology Institute

The Florey Institute of Neuroscience and Mental Health

Centre for Eye Research Australia

The Walter and Eliza Hall Institute of Medical Research

Melbourne Neuropsychiatry Centre