Utilisation of CRISPR/Cas in models of eye disease

Research Opportunity
PhD, Masters by Research, Honours, Master of Biomedical Science
Project Status
Future
Department
Surgery
Location
Surgery, Otolaryngology, Royal Victorian Eye and Ear Hospital
Supervisor Email Number Webpage
A/Prof Alex Hewitt Personal web page

Project Details

With the advent and rapid improvements in CRISPR/Cas technology, scientists have gained tools to efficiently and rapidly edit the genome. For this project, students will contribute to the development and adaptation of CRISPR/Cas tools for use in genetic diseases of the eyes. This can include, utilising the latest CRISPR in gene-editing to assess its ability to be used to correct disease-causing mutations in models for inherited eye disease; development of CRISPR/Cas constructs to be used in mouse models of eye disease; and utilisation of CRISPR screens to better understand the molecular pathways involved in the pathogenesis of eye diseases.

This project is conducted in Centre for Eye Research Australia, Clinical Genetics Group.



Faculty Research Themes

Neuroscience

School Research Themes

Neuroscience & Psychiatry



Research Opportunities

PhD, Masters by Research, Honours, Master of Biomedical Science
Graduate Research Students who are interested in joining this project will need to consider their elegibility as well as other Graduate Research requirements before contacting the supervisor of this research

View application process

Key Contact

For further information about this research, please contact a supervisor.

Department

Surgery

Research Group / Unit / Centre

Research Node

Surgery, Otolaryngology, Royal Victorian Eye and Ear Hospital