Utilisation of CRISPR/Cas in models of eye disease
- Research Opportunity
- PhD, Masters by Research, Honours, Master of Biomedical Science
- Project Status
- Surgery, Otolaryngology, Royal Victorian Eye and Ear Hospital
|A/Prof Alex Hewitt||Personal web page|
With the advent and rapid improvements in CRISPR/Cas technology, scientists have gained tools to efficiently and rapidly edit the genome. For this project, students will contribute to the development and adaptation of CRISPR/Cas tools for use in genetic diseases of the eyes. This can include, utilising the latest CRISPR in gene-editing to assess its ability to be used to correct disease-causing mutations in models for inherited eye disease; development of CRISPR/Cas constructs to be used in mouse models of eye disease; and utilisation of CRISPR screens to better understand the molecular pathways involved in the pathogenesis of eye diseases.
This project is conducted in Centre for Eye Research Australia, Clinical Genetics Group.
Faculty Research Themes
School Research Themes
PhD, Masters by Research, Honours, Master of Biomedical Science Graduate Research Students who are interested in joining this project will need to consider their elegibility as well as other Graduate Research requirements before contacting the supervisor of this research
For further information about this research, please contact a supervisor.