Transcriptome analysis in corneal disease

Research Opportunity
PhD, Masters by Research, Honours, Master of Biomedical Science
Project Status
Future
Department
Surgery
Location
Surgery, Otolaryngology, Royal Victorian Eye and Ear Hospital
Supervisor Email Number Webpage
Prof Paul Baird Personal web page

Project Details

A number of diseases that affect the clear front part of the eye called the cornea can have a significant impact on vision. In order to better understand the mechanisms behind corneal disease, we have been collecting corneal samples from patients at the time of surgery. Using these tissues as well as other patient samples, students will assess genetic differences between disease and non-disease individuals. A range of techniques including next-generation RNA sequencing and transcriptome analysis as well as RT-PCR, copy number analysis, genotyping, and epigenetics will be incorporated into this study followed by bioinformatic and functional analysis. The resultant findings will play an important role in understanding the underlying causes of corneal disease.

This project is conducted in Centre for Eye Research Australia, Ocular Genetics Group.



Faculty Research Themes

Neuroscience

School Research Themes

Neuroscience & Psychiatry



Research Opportunities

PhD, Masters by Research, Honours, Master of Biomedical Science
Graduate Research Students who are interested in joining this project will need to consider their elegibility as well as other Graduate Research requirements before contacting the supervisor of this research

View application process

Key Contact

For further information about this research, please contact a supervisor.

Department

Surgery

Research Node

Surgery, Otolaryngology, Royal Victorian Eye and Ear Hospital