NMDA receptor antagonists and cognitive dysfunction
- Research Opportunity
- PhD, Masters by Research, Honours, Master of Biomedical Science
- Project Status
- Medicine and Radiology
- Royal Melbourne Hospital
|Nigel Jones||Personal web page|
NMDA receptors are ion channels involved in many aspects of neural communication and neural plasticity. Deficits in the signalling through NMDA receptors is associated with learning and memory impairments, although the specific mechanisms underlying this consequence is not clear. Here, we attempt to isolate the specific cell types which, when suffering from NMDA receptor hypofunction, lead to higher-order cognitive dysfunction, such as impairments in working memory. We will combine transgenic mouse technologies to remove NMDA receptors from specific cell types, and observe the resultant effects on cognitive behavior.
Faculty Research Themes
School Research Themes
PhD, Masters by Research, Honours, Master of Biomedical Science Graduate Research Students who are interested in joining this project will need to consider their elegibility as well as other Graduate Research requirements before contacting the supervisor of this research
For further information about this research, please contact a supervisor.