Multi-modal interrogation of the brain using functionalised carbon micro-yarns

Research Opportunity
PhD, Masters by Research, Honours, Master of Biomedical Science
Project Status
Future
Department
Medicine and Radiology
Location
St Vincent's Hospital
Supervisor Email Number Webpage
Prof Mark Cook Personal web page
Dr Nick Apollo Personal web page

Project Details

Poor understanding of the pathophysiology of many neurological disorders is the major factor limiting new therapies for epilepsy and other neurological conditions that are often unresponsive to conventional treatments. The use of electrical stimulation to treat and study neurological disorders, such as epilepsy in particular, has made significant headway. However, there exists an entire dimension of neural information conveyed non-electrically by biomolecules such as neurotransmitters and metabolites that do not receive nearly as much attention. Additionally, current neural interface devices used to collect this information are made of rigid metals that damage tissue long term. This project aims to build soft, flexible sensors capable of simultaneous electrical and chemical interrogation of the brain. These sensors would minimise long-term neuronal damage as well as improve our understanding of many neurological conditions. We have successfully built and tested an early prototype of this sensor (electrical-sensing mode only) in one animal and the results confirmed its advantages.

The chemical-sensing mode of the sensor will be developed by Dr Nick Apollo in the School of Physics. We are seeking students with a neuroscience, biomedical engineering and material science background to evaluate and validate these sensors in vitro and, subsequently, in vivo.



Faculty Research Themes

Neuroscience

School Research Themes

Neuroscience & Psychiatry



Research Opportunities

PhD, Masters by Research, Honours, Master of Biomedical Science Graduate Research Students who are interested in joining this project will need to consider their elegibility as well as other Graduate Research requirements before contacting the supervisor of this research

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Key Contact

For further information about this research, please contact a supervisor.

Department

Medicine and Radiology

Research Node

St Vincent's Hospital