Molecular signalling pathways controlling gene expression during chronic disease progression
- Research Opportunity
- PhD, Masters by Research, Honours
- Project Status
- Medicine and Radiology
- Royal Melbourne Hospital
|Dr. Adrian Achuthanemail@example.com||Personal web page|
Inflammation is now known to be associated with many chronic diseases such as cancer, Alzheimer’s disease, obesity/type II diabetes and heart disease.
This project aims to understand molecular signalling pathways controlling the expression of genes critical for the progression of such diseases. In this project you will explore in molecular terms how a particular inflammatory cell type (macrophage/dendritic cell) can adapt to provide a pro-inflammatory environment with consequences for persistence or otherwise of these significant diseases. More specifically you will investigate how transcription factors control the expression of pro-inflammatory and anti-inflammatory cytokines. Elucidation of these molecular pathways will lead to the development of novel therapies.
Faculty Research Themes
School Research Themes
PhD, Masters by Research, Honours Graduate Research Students who are interested in joining this project will need to consider their elegibility as well as other Graduate Research requirements before contacting the supervisor of this research
For further information about this research, please contact a supervisor.