Intensive continuous monitoring of motor function in acute stroke: development of a broadband-based wearable motion detector (STROKE WATCH 3)
- Research Opportunity
- PhD, Masters by Research, Honours
- Project Status
- Medicine and Radiology
- Royal Melbourne Hospital
|A/Professor Bernard Yanfirstname.lastname@example.org||Personal web page|
|Professor Stephen Davis||Personal web page|
Acute stroke is caused by a blockage of one of the arteries in the brain resulting in interrupted blood supply. Brain cells deprived of oxygenated blood die rapidly unless blood supply is restored. The clinical manifestation is acute loss of neurological function e.g. paralysis of arms and legs. One of the milestones of modern management of acute stroke is revascularization (either by mechanically retrieving the clot or by intravenous agents) in order to unblock the blocked artery. A proportion of patients will experience recanalization (reopening) of blocked arteries with consequent recovery of arm and leg movements (motor recovery) but about 30% will deteriorate.
The monitoring of motor recovery is by clinical observation is critical in the management of stroke patients. Patients who exhibit deterioration may benefit from urgent treatment. However, the current clinical observation paradigm is time consuming and subjected to inter-observer bias. We aim to validate the clinical utility of a novel portable motion detector (STROKE WATCH 3) which allows for continuous monitoring of motor recovery in acute stroke patients.
The findings of the study may inform future decision to mandate continuous motor monitoring of patients post thrombolysis. We envisage that the study findings may lead to investigations of the STROKE WATCH 3 system in other neurological diseases e.g. Epilepsy. BENCH TO BEDSIDE - MEDICAL RESEARCH University of Melbourne at Royal Melbourne Hospital Honours/MBiomedSc Projects 2017 64 Research Plan: Human Ethics Committee approval has been obtained.
The first phase of the project has been completed with 10 healthy controls. The second phase of the project aims to study the motor function of stroke patients. We hypothesize that the motion detector (STROKE WATCH 3) is able to better detect motor function fluctuations compared to standard clinical observations. Inclusion criteria: acute stroke patients admitted to RMH Stroke Care Unit.
Methods: study subjects will wear the STROKE WATCH system on each limb for 24 hours. Accelerometry raw data will be continuously transmitted
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