HDAC6 inhibitors as a treatment for Rett syndrome: Resolving neuronal trafficking deficits

Research Opportunity
Honours
Project Status
Future
Department
Paediatrics
Location
Royal Melbourne Hospital
Supervisor Email Number Webpage
Professor John Christodoulou Personal web page
Dr Nicole Van Bergen Personal web page

Project Details

We hypothesize that correcting the cytoskeletal defect in MECP2-deficient neuronal cells using HDAC6 inhibitors that correct the is cytoskeletal defect could underlie a therapeutic solution for Rett syndrome.



Faculty Research Themes

Child Health

School Research Themes

Child Health in Medicine, Musculoskeletal



Research Opportunities

Honours
Graduate Research Students who are interested in joining this project will need to consider their elegibility as well as other Graduate Research requirements before contacting the supervisor of this research

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Key Contact

For further information about this research, please contact a supervisor.

Department

Paediatrics

Research Group / Unit / Centre

Neurodevelopmental Genomics Research

Research Node

Royal Melbourne Hospital