Understanding the acquisition and maintenance of antibodies against malaria

Research Opportunity
PhD, Masters by Research, Honours, Master of Biomedical Science
Project Status
Future
Department
Medicine and Radiology
Location
Royal Melbourne Hospital
Supervisor Email Number Webpage
Dr Jack Richards Personal web page
Dr Leanne Robinson Personal web page

Project Details

Antibody responses to malaria, or other infectious diseases, are dynamic and fluctuate over time. Traditionally, most studies of immunity only measure antibody levels at a single time point, and fail to capture the dynamic nature of these responses and changes over time that may alter people’s susceptibility to infection and disease. This study will measure antibody responses to a range of malaria antigens at regular time points in children living in malaria-endemic countries. Statistical analysis and modelling approaches will be used to examine the relationship between these responses and subsequent protection from symptomatic malaria in these children. These findings will be especially important in identifying threshold antibody concentrations that are required for protection against malaria, and in developing new serological surveillance tools to determine the prevalence of malaria infection within study populations.



Faculty Research Themes

Infection and Immunology

School Research Themes



Research Opportunities

PhD, Masters by Research, Honours, Master of Biomedical Science Graduate Research Students who are interested in joining this project will need to consider their elegibility as well as other Graduate Research requirements before contacting the supervisor of this research

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Key Contact

For further information about this research, please contact a supervisor.

Department

Medicine and Radiology

Research Group / Unit / Centre

Research Node

Royal Melbourne Hospital