The blood pressure drop makes you fall

Research Opportunity
PhD, Masters by Research, Honours, Master of Biomedical Science
Project Status
Future
Department
Medicine and Radiology
Location
Royal Melbourne Hospital
Supervisor Email Number Webpage
Prof Andrea Maier andrea.maier@unimelb.edu.au + 61383872137 Personal web page
Dr Esmee Reijnierse esmee.reijnierse@unimelb.edu.au Personal web page

Project Details

(Initial) orthostatic hypotension ((i)OH) is highly prevalent in older adults, especially in those with one or more chronic diseases. iOH is defined as a blood pressure decrease(BP) of 40 mmHg systolic blood pressure (SBP) and/or 20 mmHg diastolic blood pressure (DBP) within 15 seconds after standing up, whereas OH is classically defined as a drop in BP of at least 20 mmHg of SBP and/or 10 mmHg of DBP at 1 and 3 minutes after standing up. iOH has been shown to be most predictive for balance impairment, increased self-reported impaired standing balance and falls in geriatric outpatients. While OH diagnostics are occasionally performed in clinical practice using a sphygmomanometer, continuously measured blood pressure measurements using beat to beat analyses has not entered routine geriatric care yet.

Two student positions are available:

  • Aim project 1: Define the determinates of iOH and OH and consequences of iOH and OH in geriatric outpatients using an existing database and a validation cohort.
  • Aim project 2: Analysis of effectiveness of non-pharmacological and pharmacological interventions to counteract iOH and OH in geriatric patients. Prerequisite: intention to improve epidemiological/statistical skills, intention to write a journal article, good communication skills, capacity to work in a multidisciplinary team, pleasure to work with patients.

Research Opportunities

This research project is available to PhD, Masters by Research, Honours, Master of Biomedical Science students to join as part of their thesis.
Please contact the supervisor to discuss your options.


School Research Themes

Musculoskeletal



Key Contact

For further information about this research, please contact a supervisor.

Department

Medicine and Radiology

Research Group / Unit / Centre

@AgeMelbourne

Research Node

Royal Melbourne Hospital