Risk and resilience in schizophrenia from the perspective of brain networks

Research Opportunity
Project Status
Supervisor Email Number Webpage
Dr Andrew Zalesky
Dr Vanessa Cropley vcropley@unimelb.edu.au

Project Details

Schizophrenia is a debilitating neuropsychiatric disorder ranked among the world’s top-ten leading causes of death and disability. To date, most research in schizophrenia has focused on identifying genetic, biochemical, neurobiological, and cognitive risk factors that may lead to the illness. However, there is increasing recognition for the need to identify putative factors conferring resilience to developing the disorder.

This project will use state-of-the-art neuroimaging techniques to investigate neuroimaging-based resilience endophenotypes associated with schizophrenia. Specifically, the project will investigate brain networks, which are a comprehensive description of the brain’s internal wiring. Advances in magnetic resonance imaging (MRI) have now enabled reliable mapping of an individual's white matter network or connectome. The study will investigate brain networks in patients affected with schizophrenia, their unaffected siblings and healthy comparison subjects. Resilience endophenotypes will be identified by comparing ill individuals with their unaffected family members. The student will be involved in the development and/or application of neuroimaging tools from a brain network perspective.

Research Opportunities

This research project is available to PhD students to join as part of their thesis.
Please contact the supervisor to discuss your options.

Faculty Research Themes


School Research Themes

Neuroscience & Psychiatry

Key Contact

For further information about this research, please contact a supervisor.



Research Group / Unit / Centre