Phantom Development for Longitudinal Multi-Center Clinical Trials
- Research Opportunity
- PhD, Masters by Research, Honours, Master of Biomedical Science
- Project Status
- Medicine and Radiology
- Royal Melbourne Hospital
|Prof Roland Bammer||Personal web page|
|Prof Patricia Desmond||Personal web page|
Longitudinal imaging-based trials are associated with immense costs and huge effort for the personnel involved. Often studies continue over several years and are fraught with bias due to inevitable hardware and software upgrades and system failures. To avoid systematic bias due to changes in the imaging pipeline as well as inter-vendor and intra-vendor differences of imaging devices across trial sites, sophisticated quality assurance pipelines are usually put in place. A central piece of a good quality assurance for a trial is a reproducible quality phantom. Sadly, existing quality phantoms do not consider new contrast mechanisms that are currently used in some of these trials.
The purpose of this project is to develop a new quality phantom for MR imaging which addresses the shortcomings of other commercial phantoms. Aside from an in-depth exposure to the inner workings of imaging-based (multicenter) clinical trials and their challenges, this research project will provide students with a rich learning experience in 3D printing and MR imaging. Students will be working in a brand-new research facility at the Royal Melbourne Hospital together with clinicians, scientists and engineers. Active participation in publication in top-tier peer-reviewed journals is expected. Opportunities for commercialization and spin-offs are possible.
This research project is available to PhD, Masters by Research, Honours, Master of Biomedical Science students to join as part of their thesis.
Please contact the supervisor to discuss your options.