Bone health and its long-term predictors post bone marrow transplantation

Research Opportunity
Masters by Research, Honours, Master of Biomedical Science
Project Status
Future
Department
Medicine and Radiology
Location
Royal Melbourne Hospital
Supervisor Email Number Webpage
Prof John Wark Personal web page
Prof David Ritchie Personal web page

Project Details

Both allogeneic and autologous bone marrow transplantation (BMT) are associated with a high risk of early bone loss particularly at the femoral neck, followed by gradual improvement in bone mineral density (BMD) over the ensuing years. Approximately 50% of BMT patients may develop osteopenia or osteoporosis post-BMT.

The bone loss appears to be multifactorial in aetiology and currently the prediction of long term bone health outcomes is uncertain. In this project, the ability of parameters including patient demographics, recognised risk factors for bone loss and BMD changes at 100 days and 1 year to predict BMD and fracture outcomes at 5 years and later will be examined. This information will help in stratifying BMT patients’ long-term fracture risk and in appropriately targeting bone-protective interventions.

Research Opportunities

This research project is available to Masters by Research, Honours, Master of Biomedical Science students to join as part of their thesis.
Please contact the supervisor to discuss your options.



Faculty Research Themes

Neuroscience

School Research Themes

Neuroscience & Psychiatry, Musculoskeletal



Key Contact

For further information about this research, please contact a supervisor.

Department

Medicine and Radiology

Research Group / Unit / Centre

Bone and Mineral Research Group

Research Node

Royal Melbourne Hospital